Prevalence of Vitamin D Deficiency and Its Associated Disorders at a Tertiary Care Hospital of The Al Qassim Region of Saudi Arabia


  • Mohammad Jawaid Arif Al Rass General Hospital, Al Rass, Saudi Arabia
  • Sanjay Kumar Gupta Al Rass General Hospital, Al Rass, Saudi Arabia
  • Fahd Al Khalifah Al Rass General Hospital, Al Rass, Saudi Arabia


Vitamin D deficiency, Hospitalized, Associated Symptom, Disease, Body Mass Index


Introduction: Vitamin D is a fat-soluble vitamins which is very important for maintaining healthy bone and essential for calcium and phosphorus homeostasis. This study was conducted to find out the prevalence of vitamin D deficiency and associated disorders among patients admitted in the medical ward and associated diseases/disorders if any.

Methods: It was a hospital based retrospective study.

Results: Total 144 (75%) of patients had vitamin D deficiency. The most common symptom among patients due to vitamin D deficiency was joint pain (46%). The common disease associated with vitamin D deficiency patients was diabetes (28%) which was significantly associated (p<0.05). Vitamin D level and patient’s height were significantly associated with each other (t = 126.36, P<0.0001). Linear regression model shows significant relationship between the body mass index of the patients and their serum cholecalciferol (Vitamin- D3) level (t=10.37, P<0.05) and 95% (Constant 15.64) confidence interval level of coefficient 12.6 -18.6.

Conclusion: The study showed vitamin D deficiency was the major problem of the area , more in younger age group and common among female patients. The obesity also one of the major problem of the patients of study group and Vitamin D and calcium deficiency significantly associated with obesity.


Perez-Lopez F; Vitamin D and its implications for musculo-skeletal health in women. J Obstes Gynae., 2007; 58(2):117–137.

Holick M, Garabedian M; Vitamin D: photobiology, metab-olism, mechanism of action, and clinical applications. Am J Bone Miner Res., 2006; 83:33-43.

Chan J, Jaceldo-Siegl K, Fraser G;Serum 25hydroxyvitamin D 4. status of vegetarians, partial vegetarians, and nonvege-tarians: the Adventist Health Study-2. American Journal of Clinical Nutrition, 2009; 89(5):1686–1692.

Aloia JF, Patel M, Dimaano R, Li-Ng M, Talwar SA, Mikhail M et al.; Vitamin D intake to attain a desired serum 25-5. hydroxyvitamin D concentration. American Journal of Clini-cal Nutrition, 2008; 87(6):1952–1958.

Dawodu A, Agarwal M, Hossain M, Kochiyil J, Zayed R; Hypervitaminosis D and vitamin Ddeficiency in exclusively breast feeding infants and their mother insummer: a justifi-cation for vitamin D supplementation of breast-feeding in-fants. J Pediatr., 2003; 142(2):169–173.

Kamycheva E, Joakimsen R, Jorde R; Intakes of Calcium and Vitamin DPredict Body Mass Index in the Population of Northern Norway. J Nutr.; 2003; 133(1):102–106.

Abdulkareem O. Alsuwaida et al . Prevalence of vitamin D deficiency in Saudi adults. Saudi Med J 2013; 34: 814-818

Hirani V, Mosdol A, Mishra G; Predictors of 25-hydroxyvitamin D statusamong adults in two British na-tional surveys. Br J Nutr.; 2009; 101(5):760–764.

Al-Othman A, Al-Musharaf S, Al-Daghri A, Krishnaswa-myS,Yusuf D, Alkharfy K et al.; Effect of physical activity and sun exposure on vitamin D status of Saudi children and adolescents. BMC Pediatric, 2012; 12:92-98

DeLuca HF. Overview of general physiologic features and functions of vitamin D. Am J ClinNutr 2004; 80: S1689S1696.

Martins D, Wolf M, Pan D, Zadshir A, Tareen N, Thadhani R, et al. Prevalence of cardiovascular risk factors and the se-rum levels of 25-hydroxyvitamin D in the United States: da-ta from the Third National Health and Nutrition Examina-tion Survey. Arch Intern Med 2007; 167: 1159-1165.

Giovannucci E. The epidemiology of vitamin D and cancer incidence and mortality: a review (United States). Cancer Causes Control 2005; 16: 83-95.

Elsammak MY, Al-Wossaibi AA, Al-Howeish A, Alsaeed J. Highprevalence of vitamin D deficiency in the sunny East-ern regionof Saudi Arabia: a hospital-based study. East Mediterr Health J2011; 17: 317-322.

Naeem Z, Almohaimeed A, Sharaf FK, Ismail H, Shaukat F,Inam SB. Vitamin D status among population of Qassim-Region, Saudi Arabia. Int J Health Sci (Qassim) 2011; 5:116-124.

Ardawi MS, SibianyAM, Bakhsh TM, Qari MH, Maima-niAA. High prevalence of vitamin D deficiency among healthySaudi Arabian men: relationship to bone mineral density,parathyroid hormone, bone turnover markers, and lifestylefactors. OsteoporosInt 2012; 23: 675-686.

Sadat-Ali M, AlElq A, Al-Turki H, Al-Mulhim F, Al-Ali A.Vitamin D levels in healthy men in eastern Saudi Arabia. AnnSaudi Med 2009; 29: 378-382.

Mahdy S, Al-Emadi SA, Khanjar IA, Hammoudeh MM,Sarakbi HA, Siam AM, et al. Vitamin D status in health careprofessionals in Qatar. Saudi Med J 2010; 31: 74-77.

Ginde AA, Sullivan AF, Mansbach JM, Camargo CA Jr.Vitamin D insufficiency in pregnant and nonpregnant womenof childbearing age in the United States. Am J Ob-stetGynecol 2010; 202: 436.e1-e8.

Sim JJ, Lac PT, Liu IL, Meguerditchian SO, Kumar VA, Ku-jubuDA, et al. Vitamin D deficiency and anemia: a cross-sectionalstudy. Ann Hematol 2010; 89: 447-452.

Yoon JW, Kim SW, Yoo EG, Kim MK. Prevalence and risk-factors for vitamin D deficiency in children with iron defi-ciencyanemia. Korean J Pediatr 2012; 55: 206-211




How to Cite

Arif MJ, Gupta SK, Khalifah FA. Prevalence of Vitamin D Deficiency and Its Associated Disorders at a Tertiary Care Hospital of The Al Qassim Region of Saudi Arabia. Natl J Community Med [Internet]. 2017 Nov. 30 [cited 2023 Sep. 25];8(11):654-7. Available from:



Original Research Articles

Most read articles by the same author(s)

1 2 > >>