Prevalence of Dental Fluorosis among 6-18-Year-Olds in Vidarbha, Maharashtra, and Its Association with Geological and Geochemical Fluoride Levels: A Cross-Sectional Study
DOI:
https://doi.org/10.55489/njcm.160120254706Keywords:
Fluoride, Dental Fluorosis, Children, Foodgrains, Water, Geological, GeochemicalAbstract
Background: Endemic Fluorosis is a longstanding public health problem caused by excess fluoride intake through drinking water or food products grown in soil with high fluoride content. Many areas in Maharashtra state, particularly the Vidarbha region are affected by fluorosis. The aim was to determine the prevalence of Dental Fluorosis in children of the age group of 6-18 years and corelate it with the fluoride levels in water, soil and foodgrains.
Methods and Materials: A cross-sectional study will be conducted in randomly selected villages from Vidarbha region using multistage sampling. A total sample of 1230 children aged 6-18 years will be obtained. Dean`s index will be utilized for determining the prevalence of Dental Fluorosis. Fluoride levels of drinking water, soil and foodgrains will be analyzed.
Results: The salient feature of the study is the fluoride levels in the drinking water and locally grown staple foodgrains like rice, jowar and wheat etc. This will generate evidence that corroborates with the fluorosis levels observed in the selected study region.
Conclusion: The study will be a landmark in nearly a decade providing a comparative account of Dental Fluorosis in villages with high-to-moderate endemicity and co-relate clinical manifestations with fluoride levels in water, soil and foodgrains.
References
Wei W, Pang S, Sun D. The pathogenesis of endemic fluorosis: Research progress in the last 5 years. Journal of cellular and molecular medicine. 2019;23(4):2333-2342. DOI: https://doi.org/10.1111/jcmm.14185 PMid:30784186 PMCid:PMC6433665
Malinowska E, Inkielewicz I, Czarnowski W, & Szefer P. Assessment of fluoride concentration and daily intake by human from tea and herbal infusions. Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association. 2008;46(3):1055-1061. DOI: https://doi.org/10.1016/j.fct.2007.10.039 PMid:18078704
Yang C, Zhang M, Li Y, Wang Y, Mao W, Gao Y, & Xu H. Streptozotocin Aggravated Osteopathology and Insulin Induced Osteogenesis Through Co-treatment with Fluoride. Biological trace element research, 2015;168(2):453-461. DOI: https://doi.org/10.1007/s12011-015-0374-8 PMid:26018496
Wei N, Dong Y T, Deng J, Wang Y, Qi X L, Yu W F, Xiao Y, Zhou J J, & Guan Z Z. Changed expressions of N-methyl-d-aspartate receptors in the brains of rats and primary neurons exposed to high level of fluoride. Journal of trace elements in medicine and biology: organ of the Society for Minerals and Trace Elements (GMS). 2018;45:31-40. DOI: https://doi.org/10.1016/j.jtemb.2017.09.020 PMid:29173480
GOI 2018. National programme for prevention and control of fluorosis (NPPCF) Available at: https://mohfw.gov.in/?q=major-programmes/other-national-health-programmes/national-programme-prevention-and-control-fluorosis-nppcf Accessed Dec 23, 2024
Grandjean P. Developmental fluoride neurotoxicity: an updated review. Environmental health: a global access science source. 2019;18(1):110. DOI: https://doi.org/10.1186/s12940-019-0551-x PMid:31856837 PMCid:PMC6923889
Susheela A K, Bhatnagar M, Vig K, Mondal N K. Excess fluoride ingestion and thyroid hormone derangements in children living in Delhi, India. Fluoride. 2005; 38(2):98-108. https://fluoridealert.org/wp-content/uploads/susheela-2005.pdf
Trivedi M H, Verma R J, Chinoy N J, Patel R S, Sathawara N G. Effect of high fluoride water on intelligence of school children in India. Fluoride. 2007;40(3):178-83.
Khandare A L, Gourineni S R, & Validandi V. Dental fluorosis, nutritional status, kidney damage, and thyroid function along with bone metabolic indicators in school-going children living in fluoride-affected hilly areas of Doda district, Jammu and Kashmir, India. Environmental monitoring and assessment. 2017;189(11):579. DOI: https://doi.org/10.1007/s10661-017-6288-5 PMid:29063198
Miranda G H N, Alvarenga M O, Ferreira M K, Puty B, Bittencourt L O, Fernandes Fagundes N C, Pessan J P, Rabelo B, Lima R R. A systematic review and meta-analysis of the association between fluoride exposure and neurological disorders. Sci Rep 2021.11: 22659. DOI: https://doi.org/10.1038/s41598-021-99688-w PMid:34811523 PMCid:PMC8609002
Shivaprakash P K, Ohri K, Noorani H. Relation between dental fluorosis and intelligence quotient in school children of Bagalkot district. Journal of the Indian Society of Pedodontics and Preventive Dentistry. 201;29(2):117-120. DOI: https://doi.org/10.4103/0970-4388.84683 PMid:21911949
Saravanan S, Kalyani C, Vijayarani M, Jayakodi P, Felix A, Nagarajan S, Arunmozhi P, & Krishnan V. Prevalence of dental fluorosis among primary school children in rural areas of chidambaram taluk, cuddalore district, Tamil Nadu, India. Indian journal of community medicine. 2008: official publication of Indian Association of Preventive & Social Medicine, 33(3), 146-150. DOI: https://doi.org/10.4103/0970-0218.42047 PMid:19876473 PMCid:PMC2763668
Latha S S, Ambika S R, Prasad S J. Fluoride contamination status of groundwater in Karnataka. Curr Sci. 1999;76(6):730-4.
Fawell J, Bailey K, Chilton J, Dahi E, Fewtrell, L, Magara Y. (eds.) Fluoride in Drinking-water. 2006. World Health Organization titles with IWA Publishing., pp. 63-7.
Naik R G, Dodamani A S, Vishwakarma P, Jadhav H C, Khairnar M R, Deshmukh M A, Wadgave U. Level of Fluoride in Soil, Grain and Water in Jalgaon District, Maharashtra, India. Journal of clinical and diagnostic research:JCDR. 2017;11(2):ZC05-ZC07. DOI: https://doi.org/10.7860/JCDR/2017/23223.9175 PMid:28384970 PMCid:PMC5376803
Khairnar M R, Dodamani A S, Jadhav H C, Naik R G, & Deshmukh M A. 2015. Mitigation of Fluorosis - A Review. Journal of clinical and diagnostic research : JCDR. 2015;9(6):ZE05-ZE9. DOI: https://doi.org/10.7860/JCDR/2015/13261.6085 PMid:26266235 PMCid:PMC4525626
Golgire G M, Shetti S S, Patil A, Khairnar M, Varekar A. Estimation of Fluoride Level in Drinking Water and Prevalence of Dental Fluorosis in Vairag Village of Solapur District, Maharashtra, India: A Cross Sectional Study. Epidemiology (Sunnyvale). 2016;6: 275. DOI: https://doi.org/10.4172/2161-1165.1000275
Dhurvey V and Marganwar R. Prevalence and severity of dental fluorosis among school students in Dongargaon of Chandrapur district, Maharashtra, India. J. Environ. Res. Develop. 2013;8(2):309-314.
Jakati S, Hazarey P V, Atram H K, and Chachada A. Mysterious prevalence of dental fluorosis in Waghdhara. International Journal of Information Research and Review. 2017;04(07):4326-4328.
Kim H Y. Statistical notes for clinical researchers: post-hoc multiple comparisons. Restorative dentistry & endodontics. 2015;40(2):172-176. DOI: https://doi.org/10.5395/rde.2015.40.2.172 PMid:25984481 PMCid:PMC4432262
Patel R M, Patel K S, Naik M L. Zr(iv)‐spadns flow analysis procedure for determination of fluoride in surface and groundwater, International Journal of Environmental Studies, 1999.56(5):745-756. DOI: https://doi.org/10.1080/00207239908711235
Marques T L, Coelho N. M. Proposed flow system for spectrophotometric determination of fluoride in natural waters. Talanta. 2013;105:69-74. DOI: https://doi.org/10.1016/j.talanta.2012.11.071 PMid:23597990
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