Mycoplasma Genitalium and Chlamydia Trachomatis Prevalence, Co-Infection and Relevant Factors in An Epidemiology Study (2016 - 2019) In Ho Chi Minh, Vietnam

Authors

  • Nguyen Ngoc Hieu Faculty of Environmental and Natural Sciences, Duy Tan University, Da Nang, 550000, Vietnam; Institute for Research and Training in Medicine, Biology and Pharmacy, Duy Tan University, Da Nang, 550000, Vietnam
  • Lam Pham Phuoc Hung HCMC Hospital of Dermato Venereology, Ho Chi Minh City, 700000, Vietnam
  • Ngo Phuoc Nguyen Ngoc Faculty of Environmental and Natural Sciences, Duy Tan University, Da Nang, 550000, Vietnam; Institute of Research and Development, Duy Tan University, Da Nang, 550000, Vietnam

DOI:

https://doi.org/10.55489/njcm.140120232503

Keywords:

Chlamydia trachomatis, Mycoplasma genitalium, sexually transmitted infections, co-infections

Abstract

Chlamydia trachomatis and Mycoplasma genitalium are two common types of sexually transmitted infections. However, currently in Vietnam, there is no report on the rate of patients infected by the two types of bacteria. In this study, there were 6194 patients visiting the STI clinic of the HCMC Hospital of Dermato-Venereology, Vietnam, from 2016 to 2019. The results show that the proportion of patients positive with CT and MG is independent on time. The infection rate is mainly at the age of 21 - 30 (53.4%). The CT infection rate in female and male is equal (17.3% vs 17.4%) while the rate of MG in female is lower (5.1% vs 7, 8%). The rate of patients co-infected with either CT or MG is 4.5%, 17% and 5.7% respectively, time independence. This study may give better understandings of the epidemiological characteristics of MG and CT in Vietnam.

References

Cotch MF, Pastorek JG, Nugent RP, Hillier SL, Gibbs RS, Martin DH, et al. Trichomonas vaginalis associated with low birth weight and preterm delivery. The vaginal infections and prematurity study group. Sexually Transmitted Diseases 1997; 24:353-360. Doi: https://doi.org/10.1097/00007435-199707000-00008 PMid:9243743

Low N, Egger M, Sterne JAC, Harbord RM, Ibrahim F, Lindblom B, et al. Incidence of severe reproductive tract complications associ-ated with diagnosed genital chlamydial infection: the Uppsala Female's Cohort Study. Sexually Transmitted Infection 2006; 82(3):212-218. Doi: https://doi.org/10.1136/sti.2005.017186 PMid:16731670 PMCid:PMC2576723

Wallin KL, Wiklund F, Luostarinen T, Ångström T, Anttila T, Bergman F, et al. A population-based prospective study of Chlamydia trachomatis infection and cervical carcinoma. International Journal of Cancer 2002; 101(4):371-374. Doi: https://doi.org/10.1002/ijc.10639 PMid:12209962

Derrick T, Roberts CH, Last AR, Burr SE, Holland MJ, Holland MJ. Trachoma and ocular chlamydial infection in the era of genomics. Mediators of Inflammation 2015; 791847. Doi: https://doi.org/10.1155/2015/791847 PMid:26424969 PMCid:PMC4573990

Grieshaber S, Grieshaber N, Yang H, Baxter B, Hackstadt T, Omsland A. Impact of Active Metabolism on Chlamydia trachomatis Ele-maletary Body Transcript Profile and Infectivity. Journal of Bacteriol 2018; 200(14): e00065-18. Doi: https://doi.org/10.1128/JB.00065-18 PMid:29735758 PMCid:PMC6018357

Malhotra M, Sood S, Mukherjee A, Muralidhar S, Bala M. Genital Chlamydia trachomatis: An update. Indian Journal of Medical Re-search 2013; 138(3): 303-316.

Braam JF, van Marm S, Severs TT, Y Belousov, Mahoney W, Kusters JG. Sensitive and specific assay for the simultaneous detection of Mycoplasma genitalium and macrolide resistance-associated mutations. European Journal of Clinical Microbiology & Infectious Diseases 2018; 37:2137-2144. Doi: https://doi.org/10.1007/s10096-018-3350-3 PMid:30276584

Jensen JS, Uldum SA, Søndergård-Andersen J, Vuust J, Lind K. Polymerase chain reaction for detection of Mycoplasma genitalium in clinical samples. Journal of Clinical Microbiology 1991; 29(1):46-50. Doi: https://doi.org/10.1128/jcm.29.1.46-50.1991 PMid:1993766 PMCid:PMC269700

Brookings C, Goldmeier D, Sadeghi-Nejad H. Sexually Transmitted Infections and Sexual Function in Relation to Male Fertility. Kore-an Journal of Urology 2013; 54(3): 149-156. Doi: https://doi.org/10.4111/kju.2013.54.3.149 PMid:23526114 PMCid:PMC3604566

Newman L, Rowley J, Hoorn SV, Wijesooriya NS, Unemo M, Low N, et al. Global estimates of the prevalence and incidence of four curable sexually transmitted infections in 2012 based on systematic review and global reporting. PLoS One 2015; 10(12):e143304. Doi: https://doi.org/10.1371/journal.pone.0143304 PMid:26646541 PMCid:PMC4672879

Huai P, Li F, Chu T, Liu D, Liu J, Zhang F. Prevalence of genital Chlamydia trachomatis infection in the general population: a meta-analysis. BMC Infectious Diseases 2020; 589(2020):1-8. Doi: https://doi.org/10.1186/s12879-020-05307-w PMid:32770958 PMCid:PMC7414538

Baumann L, Cina M, Egli-Gany D, Goutaki M, Halbeisen FS, Lohrer GR, et al. Prevalence of Mycoplasma genitalium in different popula-tion groups: systematic review andmeta-analysis. Sex Transm Infect 2018; 94(4):255-262. Doi: https://doi.org/10.1136/sextrans-2017-053384 PMid:29440466 PMCid:PMC5969327

World Health Organization. Global Health Sector Strategy on Sexually Transmitted Infections 2016-Towards Ending STIs; WHO: Geneva, Switzerland, 2016

Newman L, Rowley J, Hoorn SV, Wijesooriya NS, Unemo M, Low N, et al. Global estimates of the prevalence and incidence of four curable sexually transmitted infections based on systematic review and global reporting. PLoS ONE 2015; 10(12):e0143304. Doi: https://doi.org/10.1371/journal.pone.0143304 PMid:26646541 PMCid:PMC4672879

Chen XS, Peeling RW, Yin YP, Mabey DC. The epidemic of sexually transmitted infections in China: implications for control and future perspectives. BMC Medicine 2011; 9: 111 Doi: https://doi.org/10.1186/1741-7015-9-111 PMid:21975019 PMCid:PMC3203037

Walker J, Fairley CK, Bradshaw CS, Tabrizi SN, Chen MY, Twin J, et al. The difference in determinants of Chlamydia trachomatis and Mycoplasma genitalium in a sample of young Australian female. BMC Infect Dis 2011; 11:35. Doi: https://doi.org/10.1186/1471-2334-11-35 PMid:21284887 PMCid:PMC3038161

Horner PJ, Martin DH (2017) Mycoplasma genitalium Infection in Men. The Journal of Infectious Diseases 2017; 216(2): S396-S405. Doi: https://doi.org/10.1093/infdis/jix145 PMid:28838074 PMCid:PMC5853510

Manhart LE, Holmes KK, Hughes JP, Houston LS, Totten PA. Mycoplasma genitalium among young adults in the United States: an emerging sexually transmitted infection. Am J Public Health 2007; 97:1118-1125. Doi: https://doi.org/10.2105/AJPH.2005.074062 PMid:17463380 PMCid:PMC1874220

Getman D, Jiang A, O'Donnell M, Cohen S. Mycoplasma genitalium Prevalence, Coinfection, and Macrolide Antibiotic Resistance Fre-quency in a Multicenter Clinical Study Cohort in the United States. Journal of Clinical Microbiology 2016; 54(9): 2278-83. Doi: https://doi.org/10.1128/JCM.01053-16 PMid:27307460 PMCid:PMC5005488

Sweeney EL, Trembizki E, Bletchly C, Bradshaw CS, Menon A, Francis F, et al. Levels of Mycoplasma genitalium Antimicrobial Re-sistance Differ by Both Region and Gender in the State of Queensland, Australia: Implications for Treatmalet Guidelines. Journal of Clinical Microbiology 2019; 57(3): e01555-18. Doi: https://doi.org/10.1128/JCM.01555-18 PMid:30602443 PMCid:PMC6425175

Liang YY, Zhai HY, Li ZJ, Jin X, Chen Y, Chen SP. Prevalence of Ureaplasma urealyticum, Chlamydia trachomatis, Neisseria gonorrhoeae and herpes simplex virus in Beijing, China. Epidemiology and Infection 2019; 147:e59. Doi: https://doi.org/10.1017/S0950268818003163 PMid:30501682 PMCid:PMC6518584

Manhart LE, Aral SO, Holmes KK, Critchlow CW, Hughes JP, Whittington WLH, et al. Influence of study population on the identifica-tion of risk factors for sexually transmitted diseases using a case-control design: the example of gonorrhea. American Journal of Ep-idemiology 2014; 160(4):393-402. Doi: https://doi.org/10.1093/aje/kwh220 PMid:15286025

Vasilevsky S, Greub G, Nardelli-Haefliger D, Baud D. Genital Chlamydia trachomatis: understanding the roles of innate and adaptive immunity in vaccine research. Clinical Microbiology Reviews 2014; 27(2):346-370. Doi: https://doi.org/10.1128/CMR.00105-13 PMid:24696438 PMCid:PMC3993100

Upton A, Bissessor L, Lowe P, Wang X, McAuliffe G. Diagnosis of Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis and Mycoplasma genitalium: an observational study of testing patterns, prevalence and co-infection rates in northern New Zealand. Sexual Health 2018; 15(3):232-237. Doi: https://doi.org/10.1071/SH17110 PMid:29262291

Khryanin AA, Reshetnikov O. Detection rates of Mycoplasma genitalium and Chlamydia trachomatis infections in Novosibirsk, Sibe-ria, in 2010-2011. Sex Transm Infect 2012; 88(6):469. Doi: https://doi.org/10.1136/sextrans-2012-050596 PMid:22661633

de Jong AS, Rahamat-Langendoen JC, van Alphen PTW, Hilt N, van Herk CMC, Pont SBEH, et al. Large two-centre study into the preva-lence of Mycoplasma genitalium and Trichomonas vaginalis in the Netherlands. Int J STD AIDS 2016; 27(10):856-60. Doi: https://doi.org/10.1177/0956462415596496 PMid:26199286

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Published

2023-01-31

How to Cite

1.
Ngoc Hieu N, Pham Phuoc Hung L, Phuoc Nguyen Ngoc N. Mycoplasma Genitalium and Chlamydia Trachomatis Prevalence, Co-Infection and Relevant Factors in An Epidemiology Study (2016 - 2019) In Ho Chi Minh, Vietnam. Natl J Community Med [Internet]. 2023 Jan. 31 [cited 2024 Dec. 3];14(01):65-70. Available from: https://njcmindia.com/index.php/file/article/view/2503

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Short Research Article