Otosyphilis In An HIV-Infected Patient: The First Case in Vietnam

Authors

  • Pham Phuoc Hung Lam Ho Chi Minh City Hospital of Dermato-Venereology, Ho Chi Minh City, 700000, Vietnam
  • Tam Thanh Nguyen Ho Chi Minh City Hospital for Tropical Diseases, Ho Chi Minh City, 700000, Vietnam
  • Nguyen Ngoc Hieu Faculty of Environmental and Natural Sciences, Duy Tan University, Da Nang, 550000, Vietnam; Institute for Research and Training in Medicine, Biology and Pharmacy, Duy Tan University, Da Nang, 550000, Vietnam

DOI:

https://doi.org/10.55489/njcm.140220232622

Keywords:

syphilis, otosyphilis, neurosyphilis, HIV, sudden hearing loss

Abstract

Syphilis has been re-emerging around the world, especially in MSM and people living with HIV. Because of the high number of infections, complications of the disease that were previously rare, now appear again. Otosyphilis is one of them. We reported a case of a 31-year-old MSM patient, HIV-positive, with sudden hearing loss of both ears and tinnitus due to syphilis. This is the first case of otosyphilis detected in Vietnam. The diagnosis of otosyphilis may be delayed because its symptoms are similar to those of other diseases. Therefore, there should be a highly suspected indicator of otosyphilis that can help clinicians orient the diagnosis and handle it in a timely manner.

References

O'Byrne P, MacPherson P. Syphilis. BMJ 2019; 365: l4159. Doi: https://doi.org/10.1136/bmj.l4159 PMid:31253629 PMCid:PMC6598465

Abdul KA, Silva L, Perez J. A Rare Cause of Acute Bilateral Hearing Loss: Otosyphilis. Cureus 2020; 12(10): e11243

Song JJ, Lee HM, Chae SW, Hwang SJ. Bilateral otosyphilis in a patient with HIV infection. Eur Arch Otorhinolaryngol 2005; 262: 972-974. Doi: https://doi.org/10.1007/s00405-005-0934-1 PMid:15968568

de Goffau MJ, Doelman JC, van Rijswijk JB. Unilateral Sudden Hearing Loss Due to Otosyphilis. Clinics and Practice 2011; 1:e133. Doi: https://doi.org/10.4081/cp.2011.e133 PMid:24765374 PMCid:PMC3981434

Theeuwen H, Whipple M, Litvack JR. Otosyphilis: Resurgence of an Old Disease. The Laryngoscope 2018; 00: 1-5. Doi: https://doi.org/10.1002/lary.27635 PMid:30592050

World Health Organization Grades of hearing impairment: http://www.who.int/pbd/deafness/hearing_impairment_grades/en/index.html [accessed on 5 June 2008]

Mishra S, Walmsley SL, Loutfy MR, Kaul R, Logue KJ, Gold WL. Otosyphilis in HIV-Coinfected Individuals: A Case Series from Toronto, Canada. AIDS Patient Care and STDs. 2008; 22(3): 213-219. Doi: https://doi.org/10.1089/apc.2007.0019 PMid:18290755

Chan SY, Medhi M, Ekbote A, Moses S, Sibtain N, et al. Syphilis causing hearing loss. International Journal of STD & AIDS 2008; 19(10): 721-722. Doi: https://doi.org/10.1258/ijsa.2008.008124 PMid:18824631

Copeland MJ, Timpone JG, Kim HJ, Kumar PN. Clinical Characteristics and Outcomes of Patients with Otosyphilis and HIV Infection. Open Forum Infect Dis 2017 Fall; 4(Suppl 1): S668. Doi: https://doi.org/10.1093/ofid/ofx163.1784 PMCid:PMC5630703

Mckenzie BJ, Loock JW. Otosyphilis and HIV: therapeutic dilemma and outcome of treatment. BMJ Case Rep 2009: bcr01.2009.1464. Doi: https://doi.org/10.1136/bcr.01.2009.1464 PMid:21998618 PMCid:PMC3027662

Ghanem KG. Neurosyphilis: a historical perspective and review. CNS neuroscience & therapeutics 2010, 16 (2010) e157-e168. Doi: https://doi.org/10.1111/j.1755-5949.2010.00183.x PMid:20626434 PMCid:PMC6493817

Marra CM, Maxwell CL, Smith SL, Lukehart SA, Rompalo AM, et al. Cerebrospinal Fluid Abnormalities in Patients with Syphilis: Association with Clinical and Laboratory Features. The Journal of Infectious Diseases. 2004; 189(3): 369-376. Doi: https://doi.org/10.1086/381227 PMid:14745693

Lynn WA, Lightman S. Review Syphilis and HIV: a dangerous combination. The lancet Infectious Deseases 2004; 4(7): 456-466. Doi: https://doi.org/10.1016/S1473-3099(04)01061-8 PMid:15219556

Smith ME, Canalis RF. Otologic Manifestations of AIDS: The Otosyphilis Connection. The Laryngoscope 1989; 99(4): 365-372. Doi: https://doi.org/10.1288/00005537-198904000-00001 PMid:2927212

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Published

2023-02-28

How to Cite

1.
Lam PPH, Nguyen TT, Ngoc Hieu N. Otosyphilis In An HIV-Infected Patient: The First Case in Vietnam. Natl J Community Med [Internet]. 2023 Feb. 28 [cited 2024 May 29];14(02):124-7. Available from: https://njcmindia.com/index.php/file/article/view/2622

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Section

Case Report