Study of Seroprevalence of HIV, HBV, HCV and Syphilis among Blood Donors at Tertiary Care Hospital in North Karnataka
Keywords:
Blood donors, HBV, HIV, HCV, SyphilisAbstract
Background: Transfusion transmissible infections (TTIs) such as Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), Hepatitis C Virus (HCV) and Syphilis are among the greatest threats to blood safety for the recipient. So the present study was conducted to know the prevalence and trends of TTIs.
Methods: The present study was carried out at the Blood bank at- tached to Bidar Institute of Medical Sciences Bidar. In this study donors who donated blood at blood bank during five year period were retrospectively evaluated with respect to HBV, HCV, HIV, Syphilis seroprevalance.
Results: During the five year period of study there was increase in the blood donors and decrease in the seroprevalence of transfusion transmitted transfusions. Out of 26056 blood donors, 847 had sero- logical evidence of infection. The overall seroprevalence was 3.25%. The seroprevalence was high for HBV i.e. 2.88%, followed by 0.28% for HIV, 0.04% for HCV and 0.03% for VDRL.
Conclusion: In present study there was year wise increase in the blood donations at the same time there was year wise decrease in the seroprevalence of transfusion transmitted infections. The most common transfusion transmitted infection was Hepatitis B fol- lowed by HIV then HCV and last Syphilis. The seroprevalence of transfusion transmitted infection should be decreased further.
References
Pailoor K, Keshava SM, Rai P, D'Cunha O, Lakshmi C (2015) A Retrospective Study of Screening of Common Transfusion Transmitted Infections in the Blood Bank of a Tertiary Care Centre. J Blood DisordTransfus 6:267. doi:10.4172/2155- 9864.1000267
Chandekar SA, AmonkarGP,Desai HM, Valvi N, Puranik GV. Seroprevalence of transfusion transmitted infections in healthy blood donors: A 5-year Tertiary Care Hospital ex- perience.J Lab Physicians 2017;9:283-7.
Song Y, Bian Y, Petzold M, Ung COL (2014) Prevalence and Trend of Major Transfusion-Transmissible Infections among Blood Donors in Western China, 2005 through 2010. PLoS ONE 9(4): e94528. doi:10.1371/journal.pone.0094528
WHO fact sheet on Blood safety and availability. http:// www.who.int/mediacentre/factsheets/fs279/en/ last ac- cessed on 3 March 2018.
Kotwal U, Doda V, Arora S, Bhardwaj S. Blood donor notifi- cation and counseling: Our experience from a tertiary care hospital in India. Asian J TransfusSci. 2015;9:18-22.
AmruthaKumari B, Deepa S, Venkatesha D. Blood Transfu- sions: Are They Life Saving or Transfusing Infections? Online J Health Allied Scs. 2011;10(2):7.
Agarwal N. Response rate of blood donors in the Uttara- khand region of India after notification of reactive test re- sults on their blood samples. Blood Transfus. 2014;12(1):51-3
Leena MS, Mohd. Shafee. Trend and prevalence of transfu- sion transmitted infections among blood donors in rural teaching institute, south India. Journal of Pathology of Ne- pal. 2012;2:203-6
Nilima Sawke, GK Sawke, S Chawla Seroprevalence Of Common Transfusion - Transmitted infections among Blood Donors. People’s Journal of Scientific Research 7 Vol.3(1), Jan 2010:5-7
Shaikh M, Bhople KS. Seroprevalence of Transfusion Transmitted infections in blood donors at a rural based tertiary care teaching hospital in India. IOSR Journal of Dental and Medical Sciences 2015; 14(10): 29-32.
Pallavi P, Ganesh CK, Jayshree K, Manjunath GV. Sero- prevalence and trends in Transfusion Transmitted Infec- tions among blood donors in a university hospital blood bank – A 5 year study. Indian J Hematol Blood Transfus 2011 Mar; 27(1): 1-6.
Hilda Fernandes, Prema Fancy D’souza, Pushpa Maria D’souza Prevalence of Transfusion Transmitted Infections in Voluntary and Replacement Donors. Indian J Hematol Blood Transfus (July-Sept 2010) 26(3):89–91
Ray G. Current scenario of hepatitis B and its treatment in India. J Clin Transl Hepatol 2017;5 (3): 277–296. doi: 10.14218/JCTH.2017.00024.
Khattri J, Awasthi S, Ahmed F, kumar A, Dutta S, Vyas P, Mittal A. Seroprevalence of Transfusion Transmitted Infec- tions in Healthy Blood Donors in Specific Class of Kup- puswamy’s Socio-Economic Status Scale. ActaMedica Inter- national. 26;3(2):9-14.
ShaliniSunderam ,ShilpaKarir , ShamimHaider ,S.B. Singh , Asha Kiran. Sero Prevalence of Transfusion Transmitted Infections among Blood Donors at Blood Bank of Rajendra In- stitute of Medical Sciences, Ranchi. Healthline Journal Vol- ume 6 Issue 1 (January - June 2015;36-40
Giri PA, Deshpande JD, Phalke DB, Karle LB : Seropreva- lence of transfusion transmissible infections among volun- tary blood donors at a tertiary care teaching hospital in rural area of India:J.Fam. Med. Primary Care 2012: 1:48-51
Akanksha Rawat, PreetiDiwaker, PriyankaGogoi& Bharat Singh Seroprevalence & changing trends of transfusion- transmitted infections amongst blood donors in a Regional Blood Transfusion Centre in north India. Indian J Med Res 146, November 2017, pp 642-645
Chintamani Pathak, ShivaliSehgal Evaluation of the Sero- prevalence of Transfusion Transmissible Infections among Blood Donors in a Tertiary Care Hospital of North India IJBC 2016; 8(1): 13-16
K. Padma Malini, Tami Arasi, K. Sudha, O. Shravan Kumar. Sero prevalence and trends of TTI in voluntary and re- placement blood donors in a tertiary care hospital blood bank - A 3 year retrospective study. IAIM, 2017; 4(5): 122- 127.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
The authors retain the copyright of their article, with first publication rights granted to Medsci Publications.