A Case of Malignant Low Grade Endometrial Stromal Sarcoma and Review of The Literature
Keywords:
uterine sarcoma, low grade endometrial stromal sarcomaAbstract
Low grade endometrial stromal sarcoma is a rare pelvic malignancy that arises from the endometrium. This article describes the morphological features of one such tumour discovered as finding in a hysterectomy specimen of a 32-year lady with a clinical diagnosis of dysfunctional uterine bleeding with multiple fibroids. Morphological and immunohistochemical evaluations were performed and a final diagnosis of low grade endometrial stromal sarcoma was given. This report is aimed to present a case of endometrial stromal tumor because of its rare existence and difficulties in establishing histological diagnosis.
References
Koss LG, Spiro RH. Brunschwing A. Endometrial stromal sarcoma. Surg Gynecol Obstet.1965; 121: 531-7.
Norris HJ, Taylor HB. Mesenchymal tumours of the uterus: A clinical and pathological study of 53 endometrial stromal tumours. Cancer. 1966; 19: 755-66.
Larson B, Silfersward C, Nilsson B, Pettersson F. Endometrial stromal sarcoma of the uterus: A clinical and histopathological study. The radiumhemmet series 1936-1981. Eur J Obstet Gynecol Reprod Biol 1990; 35: 239-49.
Mansi JL, Ramachandra S, Wiltshaw E Fisher C. Case Report: endometrial stromal sarcomas. Gynecol Oncol 1990; 36: 113-8.
Gadducci A, Sartori E, Landoni F, et al. Endometrial stromal sarcoma: analysis of treatment failures and survival. Gynecol Oncol 1996; 63: 247-53.
Bohr L, Thomsen CF. Low-grade stromal sarcoma: a benign appearing malignant uterine tumor; a review of current literature. Differential diagnostic problems illustrated by four cases. Eur J Obstet Gynecol Reprod Biol 1991; 39:63-9.
Katz L, Merino MJ, Sakamoto H, Schwartz PE. Endometrial stromal sarcoma: a clinicopathologic study of 11 cases with determination of estrogen and progestin receptor levels in three tumors. Gynecol Oncol 1987; 26(1): 87-97.
Fekete PS, Vellios F. The clinical and histologic spectrum of endometrial stromal neoplasms: a report of 41 cases. Int. J. Gynecol Pathol 1984; 3:198-212.
Bodner K, Bodner-Adler B, Obermair A, Windbichler G, Petru E, Mayerhofer S. Prognostic parameters in endometrial stromal sarcoma: A clinicopathologic study in 31 patients. Gynecol Oncol 2001; 81(2):160-5.
Olive E, Clement PB, Young RH. Endometrial stromal tumors. An update on a group of tumors with a protean phenotype. Adv Anat Pathol 2000; 7: 257-8.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
The authors retain the copyright of their article, with first publication rights granted to Medsci Publications.