Hormonal Whirlwinds to Emotional Echoes: The Deep-Rooted Impact of Polycystic Ovary Syndrome on Psyche and Well-Being

Neeti Patel; Ivvala Anand Shaker; Kandarp Patel; Nidhi Yogeshkumar  Mangrola

doi:10.55489/njcm.160520255258

Authors

Neeti Patel Department of Biochemistry,Parul Institute of Medical Sciences and Research, Parul University, Vadodara, India
Ivvala Anand Shaker Department of Biochemistry, Swaminarayan Institute of Medical Sciences and Research, Kalol, India
Kandarp Patel Department of Pharmacology, Kiran Medical College, Surat, India
Nidhi Yogeshkumar Mangrola Department of Community Medicine, Kiran Medical College, Surat, India

DOI:

https://doi.org/10.55489/njcm.160520255258

Keywords:

PCOS, Psychological Distress, Hormonal Imbalance, Self-Body Image, Fertility Concerns

Abstract

Background: Polycystic Ovarian Syndrome (PCOS) can be presented with physical and emotional consequences. Despite large research on the effects of hormonal imbalances on physical manifestations, psychological domains are still under a grey area. This study integrates clinical and psychosocial aspects of PCOS, leading to the development of comprehensive care approaches.

Methods: 364 women aged between 18 and 35 were involved in a cross-sectional study at a tertiary care hospital. Participants were divided into four PCOS phenotype groups, diagnosed based on Rotterdam criteria, and a control group (n=240). Psychosocial domains were analysed using the HRQL-Health-Related Quality of Life questionnaire, biochemical and hormonal parameters were assessed. Correlation was found between hormones and various domains.

Results: PCOS subjects exhibited high psychosocial stress across various domains, including emotional and fertility-related concerns. Hormonal imbalances were found to be differently associated with increased psychosocial distress, body image dissatisfaction, and menstruation-related challenges in various phenotypes (p<0.05). Moreover, financial burden and fear of developing malignancies were also linked to hormonal disturbances.

Conclusion: Hormonal whirlwinds strongly affect the psychosocial aspects of PCOS subjects. Elucidating this link will pave a path for creating personalized treatment plans that can lead to physical and psychological well-being. By involving mental health support in the regular line of treatment, healthcare providers can create a better world for women suffering from PCOS.

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