Intradermal Rabies Vaccination: Improved Economical Regimen

Authors

  • Venu Shah Smt. N.H.L. Municipal Medical College, Ahmedabad
  • Nimisha Shethwala Pramukhswami Medical College, Karamsad, Anand
  • Manish Fancy Ahmedabad Municipal Corporation, Ahmedabad
  • D V Bala Smt. N.H.L. Municipal Medical College, Ahmedabad

Keywords:

Animal bite cases, Anti Rabies Vaccine, Intra Dermal Route

Abstract

Rabies is the communicable disease which is 100% fatal. However, it is 100% preventable with timely and accurate post exposure prophylaxis. Ahmedabad Municipal Corporation is one of the selected cities in the pilot project on Prevention and Control of Human Rabies 2008–2010 that by National Center for Disease Control (NCDC), New Delhi. One of the objectives of this project is to give Anti-Rabies Vaccine (ARV) by Intra-dermal (ID) route. Present study has been carried out in ARV Clinic of V S General Hospital. Forty randomly selected animal bite cases have selected. Written consent was taken after explaining about the study and serum sample was collected on day 28 from each one of the 40 patients who have received all scheduled doses of Intra-dermal rabies vaccine. Serum samples were sent to NCDC, New Delhi for estimation of antibody titers. Adequate number of antibodies (i.e.>0.5I.U./ml) were observed in 37(92.7%) samples.

References

National Guidelines for Rabies Prophylaxis and Intradermal Administration of Cell Culture Rabies Vaccines, NICD, 2007.

Rabies in South East Asia Region, available from: http://www.searo.who.int/LinkFiles/CDS_rabies.pdf.pdf

Chhabra M, Ichhpujani RL, Bhardwaj M, Tiwari KN, Panda RC, Lal S. Safety and immunogenicity of the intradermal Thai red cross (2-2-2-0-1-1) post exposure vaccination regimen in Indian population using purified chick embryo cell rabies vaccine. Indian J Med Microbiol. 2005;23:24–8.

Beran J, Honegr K, Banzhoff A, Malerczyk C. Potency requirements of rabies vaccines administered intradermally using the Thai Red Cross regimen: investigation of the immunogenicity of serially diluted purified chick embryo cell rabies vaccine. Vaccine. 2005 Jun 10;23(30):3902-7.

Charanasri U, Meesomboon V, Kingnate D, Samuthananon P, Chaeychomsri W. Intradermal simulated rabies postexposure prophylaxis using purified chick embryo rabies vaccine. J Med Assoc Thai. 1992 Nov;75(11):639-43.

Chutivongse S, Wilde H, Benjavongkulchai M, Chomchey P, Punthawong S. Postexposure rabies vaccination during pregnancy: effect on 202 women and their infants. Clin Infect Dis.1995 Apr;20(4):818-20.

Downloads

Published

2011-09-30

How to Cite

1.
Shah V, Shethwala N, Fancy M, Bala DV. Intradermal Rabies Vaccination: Improved Economical Regimen. Natl J Community Med [Internet]. 2011 Sep. 30 [cited 2024 Nov. 29];2(02):229-32. Available from: https://njcmindia.com/index.php/file/article/view/1887

Issue

Vol. 2 No. 02 (2011)

Section

Original Research Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

The authors retain the copyright of their article, with first publication rights granted to Medsci Publications.