Verbal Autopsy of Swine Flu Confirmed Cases in Surat City
Keywords:
Swine flue, Verbal autopsy, H1N1, Oseltamivir, Death AuditAbstract
Background: Delay in seeking treatment or delayed referral to higher centre, co-morbid conditions as well as low suspicion index in the early phases of epidemic were common reasons of poor patient outcome. Objective of the study was to assess the epidemiologic characteristics and high-risk profiles among reported deaths with H1N1 influenza in Surat city.
Method: Verbal autopsy audit of 30 swine flu positive cases were carried by household visit and checking medical records from respected hospitals of Surat Municipal Corporation area as well as Tapi district.
Results: Deaths were higher among age group of 18-45 years and among male population. Out of total 30 deaths, only 4 swine flu positive patients had reported to hospital within 48 hours after onset of signs & symptoms. More than 90%% swine flu death patients did not take Oseltamivir within 48 hours after onset of signs & symptoms. Diabetes, hypertension and IHD were major co morbid conditions associated with H1N1 fatality.
Conclusion: Mortality was higher in patient having co-morbid conditions like hypertension, diabetes, and IHD. Longer interval between onset of signs and symptoms to diagnosis as well as referral and initiation of Oseltamivir may be the possible reason for higher mortality during swine flu epidemic 2017.
References
Ananthanarayan R, Paniker CKJ. Ananthanarayan and Pani-ker‟s Textbook of Microbiology. 7th ed. Hyderabad (AP): Orient Longman Private limited; 2005. P. 508-9.
International Committee on Taxonomy of Viruses. “The Universal Virus Database, version4: Influenza A”. Available from: http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/00.046.0.01.htm [last cited on 2009 July 29]
Heinen PP. “Swine influenza: a zoonosis. Available from: ( http://www.vetscite.org/publish/articles/000041/print.html)”. Veterinary Sciences Tomorrow. ISSN 1569-0830 (http://www.worldcat.org/issn/1569-0830). http://www.vetscite.org/publish/articles/000041/print.html [last cited on 2003 Sep 15].
Shinde V, Bridges CB, Uyeki TM. Triple reassortment swine influenza A (H1N1) in humans in the United States, 2005–2009. NEJM. 2009;360:2616–25.
David R. Hillyard, Novel swine-origin influenza A (H1N1) virus investigation team. N Engl J Med. 2009;360:25. [PubMed]
Cate TR, Kasel JA, Couch RB, Six HR, Knight V. Clinical trials of bivalent influenza A/New Jersey/76-A/Victoria/75 vaccines in the elderly. J Infect Dis. 1977;136:S518–25. [PubMed]
Dolin R, Wise TG, Mazur MH, Tuazon CU, Ennis FA. Im-munogenicity and reactogenicity of influenza A/New Jer-sey/76 virus vaccines in normal adults. J Infect Dis. 1977;136:S435–42. [PubMed]
Garenne, M. & Fauveau, V. Potential and limits of verbal autopsies. Bull World Health Organ 2006:84: 164.
Murray, C. J., Lopez, A. D., Feehan, D. M., Peter, S. T. & Yang, G.Validation of the symptom pattern method for ana-lyzing verbal autopsy data. PLoS Med 4, e327, doi:07-PLME-RA-0521 [pii] 10.1371/journal.pmed.0040327 (2007).
WHO verbal autopsy standards pdf file.
World health orgaisation CDC Protocol of real time ( RTPCR) for influenza (H1N1) April 2009 at CDC Atlanta, United states of America. P 1-8.
Poon LLM, Chan KH, Smith GJ, Leung CSW, Guan Y, Yuen KY, et al. Molecular detection of a novel human influen-za(H1N1) of pandemic potential by conventional and Real- time Quantitative RT-PCR assays. Clin Chem. 009;55:1555–8.
www.epid.gov.lk/web/attachments/article/146/Latest_fact_sheet_H1N1_Influenza.pdf.
Health Information.Available on www.medindia.net. Ac-cessed on Jan 26,2017.
Ministry of Health and Family Welfare, Government of In-dia. Swine Flu-Clinical management Protocol and Infection control guidelines. http://mohfw.nic.in.
Global alert and response. 10 July 2009. http://www. who.int/csr/ resources/publications/ swineflu/interim_ guidance/en/index.html.
Advice on the use of masks in the community setting in In-fluenza A (H1N1) outbreaks. World Health Organisation: Global alert and response. 3 May 2009. http://www. who.int/csr/resources/publications/Adviceusemaskscommunityrevised.pdf.
Jain S, Schimitz AM, Louie j, Druckenmiller JK Chaugh R,Deutcher M,et al. Hospitalised patients with the 2009 H1N1 Influenza in united state, April June 2009.N ENGl J Med 2009;361:1935-44.
Jadawala H, Patel K, Prasad R, Patel MJ, Rana JJ, Bansal RK. Death Audit of Swine Flu Cases in Surat city. Natl J Com-munity Med. 2015; 6(1):126-9.
Novel swine origin influenza A (H1N1) virus investiga- tion team, Dawood FS, Jain S, Finelli L, Shaw MW, Lindstrom S, et al. Emergence of novel swine origin A (H1N1) influenza virus in humans. N Engl J Med 2009; 360:2605 15.
Neuzil KM, Reed GW, Mitchel EF, Simonsen L. Griffin MR. Impact of influenza on cardiopulmonary hospitalization in pregnant women. Am J Epidemiol 1998;148:1094-102.
Poggensee G, Gilsdorf A, Buda S, Eckmanns T, Claus H,Altmann D. The first wave of pandemic influenza (H1N1) 2009 in Germany: From initiation to accelera- tion. BMC In-fec Dis 2010; 10:155
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