Sputum Smear Conversion During an Alternative Method for Providing “Directly Observed Therapy Short Course” In A Rural Setup Through Mobile Team
Keywords:
sputum, short course chemotherapy, ATT, pulmonary tuberculosisAbstract
Background: Tuberculosis is a disease as old as the history of mankind. Nothing substantial could be done by the National Tuberculosis Control Program, launched in our country about 6 decades back. According to a report in India, only 30% TB cases are diagnosed and of them only 35% take treatment for adequate duration. This study was conducted to know sputum conversion of supervised short course chemotherapy for pulmonary tuberculosis.
Methods: The study was carried out on rural patients of Bareilly district. The patients were divided in two groups. Group A received drugs under supervision and Group B took conventional domiciliary treatment. In this study supervision was done by a ‘designated’ person who was usually parents, spouse, sibling or children and if no one was available or not found intelligent enough to do this job, a friend of patient living in the village was considered.
Result: The sputum conversion was significantly faster in group A as compared to group B; but at 10th week the difference between the two groups became non-significant. The significance was further lost at 3 months, as 100% patients in both groups converted to negative and remained sputum negative at the end of 6 months.
Conclusion: The sputum conversion was significantly faster in patient received anti-tuberculosis drugs under supervision as compared to patient who took conventional domiciliary treatment. The present study further supports the fact that DOTS with daily supervision is an effective treatment for tuberculosis.
References
World Health Organization. Global Tuberculosis Control 2011: WHO Report 2011 <http://whqlibdoc.who.int/publications/ 2011/9789241564380_eng.pdf. Accessed August 20, 2012.
Geeta Krishnan K. “Case holding and treatment failure under TB Clinic operating in rural setting. I.J. of TB 1990, 37, 145.
Barnes PF et al. : The course of fever during treatment of pulmonary tuberculosis. Tubercle 1987; 68: 255-260.
Patel PG, Bala DV, Vagela SD. Correlates of Delayed Initiation of Treatment after Confirmed Diagnosis under RNTCP: A Cross Sectional Study in Ahmedabad Municipal Corporation, India; National Journal of Community Medicine 2013, 4 (4), 550-54
Wang Jie Siu et al. Tianjin TB Centre, Tianjin, PR China. Integration of tuberculosis and control programme in the primary health care in Tianjin rural area. Tubercle and Lung Disease, Vol. 77, Suppl. 2, October 1999: 69.
Zhongxian Wang, Shanghai Tuberculosis Control Centre, Shanghai 200031, PRC. One mode of DOTS implemented with success in Shanghai. Tubercle and Lung Disease, Vol. 77, Suppl. 2, October 1999: 75.
Marrero, Jose A. Valdivia, Minsap, Havana, Cuba. Experiences of DOTS in Cuba. Tubercle and Lung disease. Volume 77, Supplement 2, October 1999; 77.
Bui thi Mai, National Institute of TB Respiratory Diseases, Ha Noi, Vietnam. Case finding and treatment results of Ha Noi in 1995. Tubercle and Lung disease volume 77 supplement 2 Octorber 1999-72.
A Nehar, G. Breyer B. Shrestha, K. Feldmann et al., Directly observed intermittent short course chemotherapy in the Kathumandu Valley Tubercle and lung disease (1996) 77, 302 – 307.
P. Jagota, V. H. Balasangameshwara, M.J. Jahalakshmi and Mehter M. Islam. An alternative method of providing supervised short course chemotherapy in district tuberculous programme. Ind. J. Tub. 1997; 44:73.
Zalesky r and Abdullajev G et al.: Tuberculosis control in the Caucasus : successes and constraints in DOTS implementation. Int J Tuberc Lung Dis. 1999; 3(5) : 394-401.
Reider HL : Sputum smear conversion during directly observed treatment for tuberculosis. Tubercle and Lung Disease. 1996; 77: 124-129.
Laurinen P, Tala-Heikkila M, Ronnemaa I and Tala E. : Turku University Hospital, Finland. Directly observed treatment (DOTS) in uncooperative patients twenty year experience. Tubercle and Lung disease, Vol. 77, Suppl. 2, October 1999; 75.
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