Intrapartum Amnioinfusion in Meconium-Stained Amniotic Fluid- A Randomized Control Study in A Tertiary Care Hospital

Authors

  • Ashvin D Vachhani SMIMER, Surat
  • Jitesh M Shah SMIMER, Surat
  • Garima S Goel SMIMER, Surat
  • Meghana N Mehta SMIMER, Surat
  • Archish I Desai SMIMER, Surat
  • Malati T Dalal SMIMER, Surat

Keywords:

Amnioinfusion, Meconium, Aspiration, randomized control study

Abstract

Objective: The study was undertaken to evaluate maternal and Perinatal outcomes following transcervical intrapartum amnioin- fusion in women with meconium stained amniotic fluid.

Methods: A randomized control study was conducted on 200 women with moderate to thick meconium stained amniotic fluid during labor. Group A (study group) of 100 cases received amnio- infusion. Group B (control group) of 100 cases received standard obstetric care. Fetal heart rate monitoring was done using cardioto- cography.

Results: 66% of women were in the age group of 21-25 years. Av- erage cervical dilatation at detection of meconium and detection of meconium to delivery interval was similar in both groups. In the study group, 68% women had normal vaginal delivery as com- pared to 49% in the control group (p<0.01). Operative delivery was required in 32% and 51% cases in groups A and B respectively. Me- conium aspiration syndrome was developed in 5% cases in group A and 15% cases in group B (p=0.02, Odds ratio 0.29 (0.1-0.85)). There were no differences in Apgar scores, NICU admissions and Perinatal mortality between two groups. No any maternal compli- cations were noted due to amnioinfusion.

Conclusion: Intrapartum amnioinfusion in meconium stained am- niotic fluid is simple, safe and inexpensive intervention to reduce the rates of meconium aspiration syndrome and its complications.

References

Thakkar PA, Aiyer S. Effect of amnioinfusion on outcome of neonates born with meconium stained amniotic fluid. NJIRM Apr- Jun 2012; Vol. 3(2):86-90.

Bhatia P, Kumari R, Nangia S. Role of intrapartum trans- cervical amnioinfusion in patients with meconium stained amniotic fluid. J Obstet Gynecol Ind. Jan- Feb. 2013; 63(1): 59-63.

Wenstrom KD, Parsons MT. The prevention of meconium aspiration in labor using amnioinfusion. Obstet Gynecol. 1989; 73(4): 647-51.

Hofmeyr GJ. Amnioinfusion for meconium-stained liquor in labour. Cochrane Database Syst Rev. 2002; (1): CD000014.

Rathor AM, Singh R, Ramji S, et al. Randomized trial of amnioinfusion during labour with meconium stained am- niotic fluid. BJOG. 2002; 109(1): 17-20.

Mahomed K, Mulambo T, Woelk G, et al. The collaborative randomized amnioinfusion for meconium project (CRAMP): 2. Zimbabve. Br J Obstet Gynecol. 1998; 105(3): 309-13.

Bansal N, Gupta V, Nanda A, Chaudhary P, Tandon A, Behl N. Intrapartum amnioinfusion in meconium-stained liquor: A case- control study. J Obstet Gynecol Ind.May- Jun 2013; 63(3): 164-167.

Spong CY, Ogundipe OA, Ross MG. Prophylactic amnio- infusion for MSAF. Am J Obstet Gynecol. 1994; 171: 931- 935.

Fraser WD, Hofmeyr J, Lede R, et al. Amnioinfusion Trial Group. Amnioinfusion for the prevention of MAS. N Engl J Med. 2005; 353 (9): 909-17.

Lo KWK, Rogers M. A controlled trial of Amnioinfusion: the prevention of meconium aspiration in labor. Aust NZ J Obstet Gynecol.1993; 33: 51-54.

Eriksen N, Hostetter M, Parisi V. Prophylactic Amnioinfu- sion in pregnancies complicated by thick mecomium. Am J Obstet Gynecol.1994; 171: 1026-1030.

Cialone PR, Sherer DM, Ryan RM, Sinkin RA, Abramowicz JS. Amnioinfusion during labor complicated by particulate meconium stained amniotic fluid decreases neonatal morbidity. Am J Obstet Gynecol.1994; 170: 842- 849.

De Meeus JB, d’Halluin G, Bascou V, et al. Prophylactic in- trapartum Amnioinfusion: a controlled retrospective study of 135 cases. Eur J Obstet Gynecol Reprod Biol.1997; 72: 141-148.

Puertas A, Carillo MP, Molto L, Alvarez M, Sedeno S, Mi- randa JA. MSAF in labor: a randomized trial of prophylac- tic Amnioinfusion. Eur J Obstet Gynecol Reprod Biol.2001; 99: 33-37.

Sahu L, Indervani M. Intrapartum Amnioinfusion for me- conium stained amniotic fluid. J Obstet Gynecol Ind. 2003; 53: 345-347.

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Published

2015-09-30

How to Cite

1.
Vachhani AD, Shah JM, Goel GS, Mehta MN, Desai AI, Dalal MT. Intrapartum Amnioinfusion in Meconium-Stained Amniotic Fluid- A Randomized Control Study in A Tertiary Care Hospital. Natl J Community Med [Internet]. 2015 Sep. 30 [cited 2024 Nov. 13];6(03):442-4. Available from: https://njcmindia.com/index.php/file/article/view/1235

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Original Research Articles