Efficacy of Medical Adherence on Quality of Life Among Cardiac Patients

Authors

DOI:

https://doi.org/10.55489/njcm.150620243799

Keywords:

Medical Adherence, Cardiac Patients, Quality of life

Abstract

Background: Nonadherence is linked to poor outcomes and impaired QOL. The objective is to find out the efficacy of medical adherence on quality of life among CAD Patients.

Methodology: A descriptive cross-sectional study was conducted among 130 cardiac patients, who were coming in OPD of various urban centres of Bhopal. Data collection was done from September to October 2022 using a purposive sampling framework. Medical adherence and quality of life were assessed using self-administered MAS-CAD and WHOQOL-BREF respectively. Statistical analysis: Chi-squared test, Fisher's exact test, Kruskal Wallis and Mann Whitney test were used. The correlation between medication adherence and quality of life was analysed using the Spearman rank correlation coefficient.

Results: The majority of the participants reported high (58.0%) medical adherence and were significantly correlated with variables like gender, occupational status, level of physical activity, and surgical history. Qol (<0.001), and its domains (physical, psychological and environmental) were also significantly correlated with medical adherence.

Conclusion: Better Medical adherence was associated with a high quality of life among CAD patients. Males and Homemakers or unemployed had better medical adherence. A better understanding of the factors affecting medical adherence and quality of life is necessary.

References

Coronary Artery Disease | cdc.gov. Available from: https://www.cdc.gov/heart-disease/about/coronary-artery-disease.html

Bates, T. R., Connaughton, V. M. & Watts, G. F. Non-adherence to statin therapy: a major challenge for preventive cardiology. Expert Opin. Pharmacother. 10, 2973-2985 (2009). Doi: https://doi.org/10.1517/14656560903376186 PMid:19954271

Matsuzawa, Y. & Lerman, A. Endothelial dysfunction and coronary artery disease: assessment, prognosis, and treatment. Coron. Artery Dis. 25, 713-724 (2014). Doi: https://doi.org/10.1097/MCA.0000000000000178 PMid:25365643 PMCid:PMC4220301

WHO. Adherence to Long-Term Therapies: Evidence for Action, 2003 - PAHO/WHO | Pan American Health Organization. Available from: https://www.paho.org/en/documents/who-adherence-long-term-therapies-evidence-action-2003.

Chowdhury, R. et al. Adherence to cardiovascular therapy: a meta-analysis of prevalence and clinical consequences. Eur. Heart J. 34, 2940-2948 (2013). Doi: https://doi.org/10.1093/eurheartj/eht295 PMid:23907142

Sokol, M. C., McGuigan, K. A., Verbrugge, R. R. & Epstein, R. S. Impact of medication adherence on hospitalization risk and healthcare cost. Med. Care 43, 521-530 (2005). Doi: https://doi.org/10.1097/01.mlr.0000163641.86870.af PMid:15908846

Ho, P. M. et al. Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease. Am. Heart J. 155, 772-779 (2008). Doi: https://doi.org/10.1016/j.ahj.2007.12.011 PMid:18371492

Soleimani, M. A., Zarabadi-Pour, S., Huak Chan, Y., Allen, K.-A. & Shamsizadeh, M. Factors Associated with Hope and Quality of Life in Patients with Coronary Artery Disease. J. Nurs. Res. 30, e200 (2022). Doi: https://doi.org/10.1097/jnr.0000000000000476 PMid:35234211

Horne, R. Compliance, adherence, and concordance: implications for asthma treatment. Chest 130, 65S-72S (2006). Doi: https://doi.org/10.1378/chest.130.1_suppl.65S PMid:16840369

Nunes, V. et al. Medicines adherence: Involving patients in decisions about prescribed medicines and supporting adherence. (2009).

Lehane, E. & McCarthy, G. Intentional and unintentional medication non-adherence: a comprehensive framework for clinical research and practice? A discussion paper. Int. J. Nurs. Stud. 44, 1468-1477 (2007). Doi: https://doi.org/10.1016/j.ijnurstu.2006.07.010 PMid:16973166

Fan, M., Lyu, J. & He, P. Guidelines for data processing and analysis of the International Physical Activity Questionnaire (IPAQ).2005. URL: Zhonghua Liu Xing Bing Xue Za Zhi Zhonghua Liuxingbingxue Zazhi 35, 961-4 (2014).

Suwannapong, K., Thanasilp, S. & Chaiyawat, W. The Development of Medication Adherence Scale for Persons with Coronary Artery Disease (MAS-CAD): A Nursing Perspective. Walailak J. Sci. Technol. WJST 16, 19-25 (2019). Doi: https://doi.org/10.48048/wjst.2019.4046

Agnihotri, K., Awasthi, S., Chandra, H., Singh, U. & Thakur, S. Validation of WHO QOL-BREF instrument in Indian adolescents. Indian J. Pediatr. 77, 381-386 (2010). Doi: https://doi.org/10.1007/s12098-010-0041-1 PMid:20422328

Nejat, S., Montazeri, A., Holakouie Naieni, K., Mohammad, K. & Majdzadeh, S. R. The World Health Organization quality of Life (WHOQOL-BREF) questionnaire: Translation and validation study of the Iranian version. J. Sch. Public Health Inst. Public Health Res. 4, 1-12 (2006).

Silavanich, V., Nathisuwan, S., Phrommintikul, A. & Permsuwan, U. Relationship of medication adherence and quality of life among heart failure patients. Heart Lung 48, 105-110 (2019). Doi: https://doi.org/10.1016/j.hrtlng.2018.09.009 PMid:30384984

Alsaqabi, Y. S. & Rabbani, U. Medication Adherence and Its Association with Quality of Life Among Hypertensive Patients Attending Primary Health Care Centers in Saudi Arabia. Cureus 12, e11853 (2020). Doi: https://doi.org/10.7759/cureus.11853 PMid:33282607 PMCid:PMC7714734

Lee, Y.-M. et al. Relationships among medication adherence, lifestyle modification, and health-related quality of life in patients with acute myocardial infarction: a cross-sectional study. Health Qual. Life Outcomes 16, 100 (2018). Doi: https://doi.org/10.1186/s12955-018-0921-z PMid:29788961 PMCid:PMC5964665

Zuriati, Z., Said, F. M. & Novera, M. Predictors of Quality-of-Life Quality of Adults with Coronary Artery Disease (CAD). Proc. Ser. Health Med. Sci. 2, 204-210 (2021). Doi: https://doi.org/10.30595/pshms.v2i.247

Moryś, J. M., Bellwon, J., Höfer, S., Rynkiewicz, A. & Gruchała, M. Quality of life in patients with coronary heart disease after myocardial infarction and with ischemic heart failure. Arch. Med. Sci. 12, 326-333 (2016). Doi: https://doi.org/10.5114/aoms.2014.47881 PMid:27186176 PMCid:PMC4848348

Hung, M.-Y., Hsu, K.-H., Hung, M.-J., Cheng, C.-W. & Cherng, W.-J. Interactions among gender, age, hypertension and C-reactive protein in coronary vasospasm. Eur. J. Clin. Invest. 40, 1094-1103 (2010). Doi: https://doi.org/10.1111/j.1365-2362.2010.02360.x PMid:20718850

Luttik, M. L., Jaarsma, T., Veeger, N. J. G. M. & van Veldhuisen, D. J. For better and for worse: Quality of life impaired in HF patients as well as in their partners. Eur. J. Cardiovasc. Nurs. 4, 11-14 (2005). Doi: https://doi.org/10.1016/j.ejcnurse.2004.12.002 PMid:15718187

Najafi, M., Sheikhvatan, MD, M. & Montazeri, A. Quality of life-associated factors among patients undergoing coronary artery bypass surgery as measured using the WHOQOL-BREF. Cardiovasc. J. Afr. 20, 284-289 (2009).

Dias, C. C. et al. Acute coronary syndrome and predictors of quality of life. Rev. Port. Cardiol. Orgao Of. Soc. Port. Cardiol. Port. J. Cardiol. Off. J. Port. Soc. Cardiol. 24, 819-831 (2005).

Ghasemi, E., Mohammad Aliha, J., Bastani, F., Haghani, H. & Samiei, N. Quality of Life in Women with Coronary Artery Disease. Iran. Red Crescent Med. J. 16, e10188 (2014). Doi: https://doi.org/10.5812/ircmj.10188

Downloads

Published

2024-06-01

How to Cite

1.
Chavhan AV, Verma R, Verma M, Dixit P. Efficacy of Medical Adherence on Quality of Life Among Cardiac Patients. Natl J Community Med [Internet]. 2024 Jun. 1 [cited 2024 Jul. 3];15(06):437-43. Available from: https://njcmindia.com/index.php/file/article/view/3799

Issue

Section

Original Research Articles