Assessment Of Health Status of Successfully Treated Category I Patients Under RNTCP Program, Five Years After Treatment Completion – A Retrospective Cohort Study from A Coastal District of India
Keywords:
RNTCP, DOTS, tuberculosis, current status, NSP patientsAbstract
Background: Tuberculosis remains a major public health problem worldwide and also in India. Inspite of RNTCP being a comprehensive programme for effective management and control of tuberculosis, efficacy of DOTS regimen is questioned by private practitioners.
Methods: A retrospective cohort study was carried out in a coastal district of India to assess the health status of successfully treated Category I patients under RNTCP program, five years after treatment completion. An interview was conducted with all the available subjects at their residence using a semi-structured pre-tested interview.
Results: Out of 224 registered new sputum positive patients, 177 cases were successfully treated during the recruiting year, accounting for a success rate of 79%. Of the 177 treated patients, 118 were traceable during the study period, out of which 100 subjects had survived after 5 years and were available for the interview. Recurrence of TB was reported in 2 patients during the follow up period.
Conclusion: This five years follow up study shows a good long term success rate of TB patient’s treatment. Hence, it reaffirms the scientific basis of RNTCP policy of DOTS regimen to be the right strategy for TB control.
References
Floyd K, Wilkinson D, Gilks C. Comparison of cost ef-fectiveness of directly observed treatment (DOT) and conventionally delivered treatment for tuberculosis: ex-perience from rural South Africa. BMJ 1997; 315:1407-11.
Migliori G B, Ambrosetti M, Besozzi G, Farris B, Nutini S, Saini, et al. Cost-comparison of different management policies for tuberculosis patients in Italy. AIPO TB Study Group. Bull World Health Organ 1999; 77: 467-76.
Central TB Division. TB India 2003: RNTCP Status Re-port. Directorate General of Health Services. New Delhi, India:Ministry of Health and Family Welfare, 2003.
Bhargava A, Jain Y. The Revised National Tuberculosis Control Programme in India: Time for revision of treat-ment regimens and rapid upscaling of DOTS-plus initi-ative. The Natl Med J Ind 2008; 21(4): 187-91.
Diagnosis of smear positive pulmonary TB New guide-lines, effective from 1st April 2009. Available from http://www.tbcindia.org/pdfs/1b-Diagnosisof smear-positivepulmonary TB.pdf. (Accessed on 10th August, 2010).
Santha T, Garg R, Frieden T R, et al. Risk factors associ-ated with default, failure and death among tuberculosis patients treated in a DOTS Programme in Tiruvallur District, South India, 2000. Int J Tuberc Lung Dis 2002; 6: 780-8.
Prasad R, Verma S K, Srivastava P, Kant S, Kushwaha R A S, Kumar S. A follow up study on revised national tuberculosis control programme (RNTCP): Results from a single centre study. Lung India 2008; 25:142-4.
Verma S K , Verma S K, Kant S , Kumar S, Prasad R. A five-year follow up study of Revised National Tubercu-losis Control Programme of India at Lucknow. Indian J Chest Dis Allied Sci 2008; 50:195-7.
Jagota P, Gupta E V V, Channabasavaiah R. Fate of smear positive patients of pulmonary tuberculosis at an urban District Tuberculosis Centre, five years after treatment. Ind J Tub 1994; 41: 223-32.
Dholakia Y, Danani U, Desai C. Relapse following di-rectly observed therapy short course (DOTS)—a follow up study. Indian J Tuberc 2000; 47: 233-6.
Glynn J R, Murray J, Bester A, Nelson G, Shearer S, Son-nenberg P. High rates of recurrence in HIV-infected and HIV-uninfected patients with tuberculosis. J Infect Dis 2010; 201: 704-11.
Balasangameshwara V H, Jagota P, Channabasavaiah R. Persistent chest symptoms in smear positive pulmo-nary tuberculosis patients treated with standard and short course chemotherapy regimens under a District Tuberculosis Programme - A five year follow-up. Ind J Tub 1996; 43:143-50.
Yatin D, Danani U, Desai C. Relapse following directly observed therapy short course (DOTS): a follow-up study. Indian J Tub 2000; 47: 233-6.
Jagota P, Chandrasekaran S, Sumathi G. Follow-up of pulmonary tuberculosis patients treated with short course chemotherapy through traditional birth attend-ants. Indian J Tub 1998; 45: 89-93.
Vijay S, Balasangameswara V H, Jagannatha P S, Saroja V N, Kumar P. Treatment outcome and two and half years follow up status of new smear positive patients treated under RNTCP. Indian J Tub 2004; 51: 199-208.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
The authors retain the copyright of their article, with first publication rights granted to Medsci Publications.