Epidemiological Profile and Treatment Outcome of Childhood Tuberculosis Patients in Pune City

Authors

  • Anagha Pramod Jadhav B K L Walawalkar Rural Medical College, Sawarde
  • Sunil Madhavrao Sagare MIMSR Medical College, Latur

Keywords:

Childhood TB, treatment outcome, RNTCP

Abstract

Background: Tuberculosis (TB) is a major public health problem in India. According to the Global TB Control Report 2012, the inci- dence of childhood TB is estimated at 191 per 100 000 population. Childhood TB (for children aged <15 years) is generally consid- ered to be a good marker of transmission in the community. The present study was undertaken to analyse the epidemiological and clinical characteristics of childhood TB patients and the interrela- tionship with the treatment outcome.

Methodology: This prospective study was carried out on 198 pa- tients in the age group of 0-14 years registered in all the Tubercu- losis units of Pune city. All clinical information was extracted from the treatment cards and TB registers.

Results: 39.4% were males, 40% were aged <5 years, 80 (40.4%) had extra-pulmonary involvement and the remaining 118 were pulmonary TB patients of whom 42 (35.6%) were smear positive. Overall cured and treatment completion rate was 185(93.5%). Poor treatment outcome was reported in 10(5%) patients.7 (3.5%) pa- tients defaulted. 3 (1.5%) failure to treatment were reported.

Conclusion: Childhood TB in high burden countries requires far more attention from the researchers and TB control staff. The best means of preventing TB in childhood is by control of adult TB.

References

Park.K. Textbook of Preventive and Social Medicine, 24th ed. Jabalpur: Banarsidas Bhanot publishers; 2017:164-80.

Revised National Tuberculosis Control Programme. Availa- ble at https://www.tbfacts.org/tb-children/Accessed on Oct 10th, 2018

Global tuberculosis control: epidemiology, strategy, financ- ing. WHO Report 2009 WHO South-East Asia Region 2009. New Delhi, India 2009.p24

Satyanarayana, S, R. Shivashankar, R. P. Vashist, L. S. Chauhan, S. S. Chadha, P. K. Dewan et al. "Characteristics and programme-defined treatment outcomes among child- hood tuberculosis (TB) patients under the national TB pro- gramme in Delhi. PloS one 2009; 5(10):e13338-e13338.

Banu Rekha VV, Swaminathan S. DOTS in childhood tuber- culosis. IX National Conference of paediatric infectious dis- eases, Chennai, 2006. Available http://www.pediatriconcall.com/fordoctor/conference_abstracts/ncpid2006/Article9.a sp [Last accessed 2012 Nov 11].

Sharma Sangeeta, Sarin Rohit, Khalid U K, Singla N, Shar- ma P P, Behera D. Clinical profile and treatment outcome of Tuberculous Lymphadenitis in children using DOTS strate- gy. Indian Journal of Tuberculosis. 2010 Jan; 57(1): 4-7.

Nelliyanil, Maria.A Study Of The Socio Demografic Profile And Treatment Outcome Of Paediatric Tuberculosis Pa- tients In Bangalore Mahanagar Palike Area Indian Journal of Tuberculosis 2012;59:207-213.

Lolekha, Rangsima, Amornrat Anuwatnonthakate, Sriprapa Nateniyom, Surin Sumnapun, Norio Yamada, et al. Child- hood TB epidemiology and treatment outcomes in Thailand: a TB active surveillance network, 2004 to 2006. BMC infec- tious diseases 2008; 8(1):94.

Harries, A. D. N. J. Hargreaves, S. M. Graham, C. Mwansambo, et al. Childhood tuberculosis in Malawi: na- tionwide case-finding and treatment outcomes. The Interna- tional Journal of Tuberculosis and Lung Disease 2002; 6(5):424-431.

Sivanandan Sindhu, Mandeep Walia, et al. Factors associat- ed with treatment failure in childhood tuberculosis. Indian Pediatrics 2008; 45(9):769-771.

Hanumantappa Ramesh, A. Shoba et al. Treatment out- comes of childhood tuberculosis with DOTS strategy in Kottayam, Kerala. Indian Journal of Community Health 2013; 24(4):280-284.

Wu, Xi-Rong, Qing-Qin Yin, An-Xia Jiao, Bao-Ping Xu, Lin Sun, Wei-Wei Jiao, Jing Xiao et al. Pediatric Tuberculosis at Beijing Children’s Hospital: 2002–2010. Pediatrics 2012;130 (6): 1433-1440.

Joshi S. A study of treatment outcome of paediatric tubercu- losis patients in an urban city of central India. Int J Commu- nity Med Public Health. 2018; 5(4):1503-1508

Thakur, H. P. Characteristics of childhood tuberculosis pa- tients registered under RNTCP in Varanasi, Uttar Pradesh. Indian journal of public health 2013;57(1):36-39.

Dendup, T, T. Dorji, M. E. Edginton, A. M. V. Kumar, D Wangchuk, et al. Childhood tuberculosis in Bhutan: profile and treatment outcomes. Tuberculosis and Lung Dis- ease2013; 3(1):11-14.

Mukherjee A, Chowdhury R, Singla R, Saha I, Dutta R, Das T. Comparison between childhood and adult tuberculosis in a rural tuberculosis unit of West Bengal: A retrospective study. Lung India. 2014;3(2):116-20

Indiafacts.in. Available on: https://www.tbfacts.org/tb- children/ [Last accessed on 2019 Jan 22].

Djibuti M, Mirvelashvili E, Makharashvili N, Magee MJ. Household income and poor treatment outcome among pa- tients with tuberculosis in Georgia: a cohort study. BMC Public Health. 2014; 14:88.

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Published

2019-02-28

How to Cite

1.
Jadhav AP, Sagare SM. Epidemiological Profile and Treatment Outcome of Childhood Tuberculosis Patients in Pune City. Natl J Community Med [Internet]. 2019 Feb. 28 [cited 2024 May 2];10(02):119-23. Available from: https://njcmindia.com/index.php/file/article/view/456

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Original Research Articles