A Community-Based Trial on The Comparison of Efficacy, Safety and Cost Effectiveness of Ferrous Sulphate and Ferrous Ascorbate for Anaemia in Pregnancy In Madhya Pradesh, India

Authors

  • Manju Toppo Gandhi Medical College, Bhopal, India
  • Jeewan S Meena Gandhi Medical College, Bhopal, India
  • Devendra Gour Gandhi Medical College, Bhopal, India
  • Mugdha Kamble Gandhi Medical College, Bhopal, India
  • Keerthana S Gandhi Medical College, Bhopal, India
  • Ankit Chandak Gandhi Medical College, Bhopal, India
  • Sarjan Singh Gandhi Medical College, Bhopal, India
  • Nainshree Bhunjiya Gandhi Medical College, Bhopal, India
  • Ravindra Singh Norway India Partnership Initiative, Maternal Health, National Health Mission, Bhopal, India

DOI:

https://doi.org/10.55489/njcm.140220232583

Keywords:

Ferrous ascorbate, Ferrous sulphate, Oral iron supplementation, Antenatal mothers, Cost effective analysis

Abstract

Background: Anaemia has significant impact on health of the fetus as well as that of mother. Increased need of iron during pregnancy especially after 2nd trimester makes iron supplementation mandatory. Ferrous ascorbate is known to exist intact inside the gastrointestinal tract due to the stable chelation of iron with ascorbate. This compound does not dissociate due to any of the food inhibitors. The aim is to study the effectiveness of Ferrous Ascorbate and Ferrous sulphate in terms of compliance and cost effectiveness of management of anaemia in pregnancy.

Methodology: Study design: Quasi Experimental study, Study area: District Vidisha, Study participants: Pregnant women of first trimester registered during the study period in the selected Anganwadis/ Gram Arogya Kendra (GAK), Sample size: 240 antenatal mothers.

Results: Baseline mean haemoglobin was 11.31±1.05 gm/dl. The mean increase in Ferrous Sulphate was 0.55 gm/dl, and in Ferrous ascorbate was 1.27 gm/dl. Ferrous Sulphate was less compliant than Ferrous ascorbate, and has higher efficacy and lesser side effects. Only Rs. 10.2 additional cost per antenatal mothers for increase of ≥1gm% in Hb will be borne by government if Ferrous Sulphate is replaced by Ferrous Ascorbate.

Conclusions: Study results show statistically significant difference in rise of haemoglobin amongst the antenatal mothers consuming Ferrous ascorbate over Ferrous Sulphate.

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Published

2023-02-28

How to Cite

1.
Manju Toppo, Meena JS, Gour D, Kamble M, Keerthana S, Ankit Chandak, Sarjan Singh, Bhunjiya N, Ravindra Singh. A Community-Based Trial on The Comparison of Efficacy, Safety and Cost Effectiveness of Ferrous Sulphate and Ferrous Ascorbate for Anaemia in Pregnancy In Madhya Pradesh, India. Natl J Community Med [Internet]. 2023 Feb. 28 [cited 2024 Jun. 23];14(02):74-81. Available from: https://njcmindia.com/index.php/file/article/view/2583

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Original Research Articles