A Study on Socio-demographic Profile and Outcome of Tuberculosis in HIV-TB Co-infected Cases in Surat City, Western India

Authors

  • Vaibhav Gharat GMERS Medical College, Valsad, Gujarat
  • Bhautik P Modi GMERS Medical College, Gandhinagar, Gujarat
  • Prakash Patel SMIMER, Surat
  • Sunil Nayak GMERS Medical College, Valsad, Gujarat
  • Ajay Pawar SMIMER, Surat
  • R K Bansal SMIMER, Surat

Keywords:

HIV-TB, Co-infection, HIV, Tuberculosis, ART, AIDS

Abstract

Background: As tuberculosis is one of the most common causes of morbidity and mortality in HIV-infected individuals. The present study was planned with an objective to find out the socio-demographic profile of HIV-Tb co-infected cases.

Methodology: This was a descriptive longitudinal study of HIV TB co-infected patients registered in Revised National Tuberculosis Control Programme (RNTCP) and Anti-retroviral Therapy (ART) centre.

Results: Diagnosis of both HIV and tuberculosis at the same time was positive in 104 (51.0%) of the patients. Majority (77.0%) of the cases were having extra-pulmonary tuberculosis which includes abdominal, lymph node, inguinal nodes, etc. Sputum positivity was seen in 22 (34.4%) of the cases. Radiological findings were significant in 24.5% of the cases HIV Tb co-infected cases. It was found 146 (75.6%) of the cases had favourable outcome i.e., cure and treatment completed.

Conclusion: It was observed that 75.6% of the cases of the HIV-TB co-infected cases had a favourable outcome (cured and treatment completed). Active case finding of Tuberculosis should be done in HIV cases as we observed 51% cases having TB and HIV diagnosed simultaneously.

References

S. Swaminathan, R. Ramachandran, G. Baskaran, C. N. Par-amasivan, U. Ramanathan, P. Venkatesan, R. Prabhakar, M. Datta. (2000) Risk of development of tuberculosis in HIV-infected patients. Int j tuberc lung dis. 4(9):839–844.

Godfrey-Faussett P, Maher D, Mukadi YD, Nunn P, Per-riens J, Raviglione M. (2002) How human immunodefi cien-cy virus voluntary testing can contribute to tuberculosis control. Bull World Health Organ; 80: 939–45.

Nachega J, Coetzee J, Adendorff T, et al. (2003) Tuberculosis active casefinding in a mother-to-child HIV transmission prevention programme in Soweto, South Africa. AIDS; 17: 1398–400.

Burgess AL, Fitzgerald DW, Severe P, et al. (2001) Integra-tion of tuberculosis screening at an HIV voluntary counsel-ling and testing centre in Haiti. AIDS; 15: 1875–79.

Benson CA, Kaplan JE, Masur H, Pau A, Holmes KK. (2004) Treating opportunistic infections among HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the Infectious Diseases Society of America. MMWR Recomm Rep; 53: 1–112.

Elliott AM, Namaambo K, Allen BW, et al. (1993) Negative sputum smear results in HIV-positive patients with pulmo-nary tuberculosis in Lusaka, Zambia. Tuber Lung Dis; 74: 191–94.

Williams BG, Dye C. (2003) Antiretroviral drugs for tuber-culosis control in the era of HIV/AIDS. Science; 301: 1535–37.

Sophia Vijay, Prahlad Kumar, Lakbir Singh Chauhan, Saroja Vadigepalli Narayan Rao, and Preetish Vaidyanathan. (2011) Treatment Outcome and Mortality at One and Half Year Follow-Up of HIV Infected TB Patients Under TB Con-trol Programme in a District of South India. PLoS One.; 6(7): e21008.

Ragini Ghiya, Eknath Naik, Beata Casanas, Ricardo Izurieta, and Yogesh Marfatia. (2009) Clinico-epidemiological profile of HIV/TB coinfected patients in Vadodara, Gujarat Indian J Sex Transm Dis. Jan-Jun; 30(1): 10–15.

Jiang Xueyan et al. (2008) A Cross-Sectional Study of HIV and Tuberculosis Coinfection Cases in Mainland China. Southern Medical Journal Volume 101, Number 9, Septem-ber 2008. 914-17.

Harries AD, Nyangulu DS, Kang’ombe C, Ndalama D, Glynn JR, Banda H, et al. (1998) Treatment outcome of an unselected cohort of tuberculosis patients in relation to human immunodeficiency virus serostatus in Zomba Hos-pital, Malawi. Trans R Soc Trop Med Hyg. 1998;92(3):343-7.

Oliveira HB, Marin-León L, Gardinali J. (2005) Analysis of treatment outcomes related to the tuberculosis control pro-gram in the city of Campinas, in the state of São Paulo, Bra-zil. J Bras Pneumol;31(2):133-8.

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Published

2017-12-31

How to Cite

1.
Gharat V, Modi BP, Patel P, Nayak S, Pawar A, Bansal RK. A Study on Socio-demographic Profile and Outcome of Tuberculosis in HIV-TB Co-infected Cases in Surat City, Western India. Natl J Community Med [Internet]. 2017 Dec. 31 [cited 2024 Dec. 22];8(12):755-8. Available from: https://njcmindia.com/index.php/file/article/view/1827

Issue

Vol. 8 No. 12 (2017)

Section

Original Research Articles

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