Smoking, Smokeless Tobacco Consumption & Coronary Artery Disease – A Case Control Study
Keywords:
Case Control study, Coronary artery disease, Smoking, Smokeless tobaccoAbstract
Background: Coronary artery disease (CAD) is a major cause of premature death and disability throughout the world. Tobacco use is an important and avertable cause of CAD. The use of tobacco is on the rise worldwide. Present study was carried out to study the role of tobacco consumption in the occurrence of Coronary artery disease.
Materials and Methods: Present study was a hospital based paired matched case-control study, carried out at civil hospital, Ahmedabad. 135 newly diagnosed cases of coronary artery disease and 135 controls were studied after taking informed written consent. Data was analyzed by using Epi-info version 3.5.1 computer package, Chi -square test, Z test and Odds ratio was calculated.
Results: Among the total 135 cases 70.4% were male and 29.6% were female, most of the cases (40%) were belongs to the age group of 51-60 years. Smokers and smokeless tobacco users were significantly higher among the cases as compared to controls. Significant association was also observed between current smokers, smokeless tobacco users and Coronary artery disease. Strong associations were also observed between frequency and duration of smoking with CAD.
Conclusion: Tobacco consumption in any form is major aetiology behind the occurrence of CAD.
References
Reddy KS, Yusuf S. Emerging epidemic of cardiovascular disease in developing countries. Circulation. 1998; 97(6):596-601.
Gupta R. Burden of Coronary Heart Disease in India. Indian heart J. 2004; 57:632-638.
Prevention of Coronary heart Disease. Tech. Rep. Ser., WHO. 1982;678.
Wilhelmsson C. Risk factors of coronary artery disease. Lancet 1975; 1: 415.
National family health survey (NFHS III). India, 2005- 2006.
David G Kleinbaum, Kevin M Sullivan, Nancy D Barker. Active Epi Companion Textbook: A supplement for use with active Epi CD-ROM.
Tunstall-Pedoe H, Kuulasmaa K, AmouyelP, Arveiler D, Rajakangas AM, Pajak A. Myocardial infarction and coronary deaths in the World Health Organization MONICA Project. Registration procedures, event rates, and case-fatality rates in 38populations from 21countries in four continents. Circulation 1994;90:583-612
Sanjay P Zodpey, Hemant R Kulkarni, N. D Vasudeo, S. W Kulkarni. Risk factors for coronary heart disease: A case control study. Indian journal of community medicine.1998;23:7-14.
Fichenberg CM, et al. Association of California Tobacco Control Progarm with declines in cigarette consumption and mortality from heart disease. N Engl J Med 2000; 343: 1772-1777.
Yathish TR, Manjula CG, Srinivas R Deshpande, Gayathree L. Coronary artery disease, Cigarette smoking, Rose angina questionnaire and Rose smoking questionnaire. JCDS April 2001;5(2):264-268
Pais P, Pogue J, Gerstein H. Risk factors for acute myocardial infarction in Indians: a case-control study. Lancet 1996; 348: 358-363.
Subrata Bagchi, Ranadeb Biswas, Uchhal K. Bhadra, Anirudda Roy, Malay Mundle, Pradip Kr Dutta. Smoking, Alcohol Consumption & Coronary Heart Disease- A Risk Factor Study. Indian Journal of Community Medicine Oct-Dec 2001; 26(4):208-211.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
The authors retain the copyright of their article, with first publication rights granted to Medsci Publications.
