Predictive Value of Various Risk Factors for Preterm Labor

Authors

  • Purvi K Patel Medical College Baroda, Vadodara
  • Dipa S Pitre Medical College Baroda, Vadodara
  • Suman P Bhooker Medical College Baroda, Vadodara

Keywords:

Preterm, labor, predictive value, pregnancy

Abstract

Objective: The objectives of this study were to study the various etiological factors responsible for onset of preterm labor and to evaluate the predictive value of these risk factors for spontaneous preterm labor.

Methods: This prospective comparative study was conducted over a period of 1 year and included 240 women; of which 120 in preterm labor were enrolled in the study group and 120 with term pregnancy in labor were enrolled in the control group. History, clinical examination and investigations were carried out and risk factors for preterm labor were noted and analyzed to find out the predictive value of the risk factors for preterm labor.

Results: Maximum numbers of patients (31.6%) were in the 35-36 weeks gestational age group. When both the groups were compared as regards risk factors, the cases showed a high incidence of infections; 21.7% incidence of chorioamnionitis, 32.5% incidence of bacterial vaginosis and a 12.5% incidence of urinary tract infections. Prior second trimester abortion was found in 13.3% cases and a history of prior preterm birth was found in 15% cases. Uterine over distension was observed in 20.83% cases. Maternal medical disorders were present in 60% cases.

Conclusions: Multiple pregnancy, Prior preterm birth, Infections, Prior second trimester abortions and medical disorders in mother are strongly associated with an increased risk of preterm labor.

References

Kore S J, Rao S, Bhagwat A, Gujarati P et al. Predic-tion of preterm labor by transvaginal sonography. Bombay hospital journal 2004.

Dasgupta S. Preterm labor. In; Immunological basis of pathophysiology. Mukherjee OG, Buckshee K edi-tors, 1st edition, 1998;4-7.

KS Joseph, John Fahey, Ketan Shankerdass et al. Ef-fects of socio-economic position and clinical risk fac-tors on spontaneous and iatrogenic preterm birth. BMC Pregnancy and Childbirth 2014, 14:117

Berkowitz G, Papiernik E. Epidemiology of preterm birth. Epidemiol Rev 1993;15:414 – 443.

Lawson CC, Whelan EA, Hibert EN, Grajewski B, Spiegelman D, Rich-Edwards JW Occupational fac-tors and risk of preterm birth in nurses. Am J Obstet Gynecol. 2009;200(1):51.e1.

Honest H, Bachmann LM, Ngai C, Gupta JK, Kleijnen J, Khan KS The accuracy of maternal anthropometry measurements as predictor for spontaneous preterm birth--a systematic review. Eur J Obstet Gynecol Re-prod Biol. 2005;119(1):11.

Spong CY. Prediction and prevention of recurrent spon- taneous preterm birth. Obstet Gynecol 2007;110:405–15.

Boyd HA, Poulsen G, Wohlfahrt J, Murray JC, Feenstra B, Melbye M Maternal contributions to pre-term delivery. Am J Epidemiol. 2009;170(11):1358.

Blondel B, Dutilh P, Delour M, Uzan S. Poor antena-tal care and preg- nancy outcome. Eur J Obstet Gyne-col Reprod Biol 1993;50:191 – 196.

CV Ananth, AM Vintzileos. Maternal-fetal conditions necessitating a medical intervention resulting in pre-term birth. Am J Obstet Gynecol. 2006;195(6):1557-1563.

Goldenberg RL, Culhane JF, Iams JD, Romero R. Epi-demiology and causes of preterm birth. The Lancet 2008; 371:75-84.

Jasovic-Siveska E (2014) Prevention and Prediction of Preterm Birth-Status Quo in the Last 50 Years. Re-prod Syst Sex Disord 3:e117. doi: 10.4172/2161-038X.1000e117

Yoon BH, Romero R, Moon JB, et al. Clinical signifi-cance of intra-amniotic inflammation in patients with preterm labor and intact membranes. Am J Obstet Gynecol. 2001;185:1130.

Lamont RF. Infection in prediction and antibiotics in prevention of spontaneous preterm labor and preterm birth. BJOG;2003: 110(2):71-5.

Glantz JC. Screening and treatment of bacterial vagi-nosis during pregnancy; a model for determining ben-efit. Am J Perinatol 1997;14:487-90.

Hillier SL, Nugent RP, Eschanbach DA et al. Associa-tion between bacterial vaginosis and preterm delivery of a low birth weight infant. The vaginal infections and prematurity study group. N Engl J Med 1995; 333: 1737-42.

Meis PJ, Goldenberg RL, Mercer B et al. The preterm prediction study: significance of vaginal infections. Am J Obstet Gynecol 1995; 173: 1231-5.

Leitich H, Bodner-Adler B, Brunbauer M, Kaider A, Egarter C, Husslein P. Bacterial vaginosis as a risk factor for preterm delivery: a meta-analysis. Am J Obstet Gynecol 2003;189:139 – 147.

Beverly A, Von Der Pool. Preterm labor: diagnosis and treatment-problem oriented diagnosis. American Family Physician 1998; 57 (may 15):10.

Chang HH, Larson J, Blencowe H, Spong CY, Howson CP, et al. Preventing preterm births: analysis of trends and potential reductions with interventions in 39 countries with very high human development index. Lancet 2013;381: 223-234.

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Published

2015-03-31

How to Cite

1.
Patel PK, Pitre DS, Bhooker SP. Predictive Value of Various Risk Factors for Preterm Labor. Natl J Community Med [Internet]. 2015 Mar. 31 [cited 2024 Apr. 25];6(01):121-5. Available from: https://njcmindia.com/index.php/file/article/view/1144

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Original Research Articles