Assessment of 10-Year Risk of Developing a Major Cardiovascular Event in Type-2 Diabetes Patients Attending a Hospital in Davangere, Karnataka
Keywords:
Diabetes, Cardiovascular disease, stroke, CVD, risk, WHO-ISHAbstract
Background: Diabetes increases the risk of cardiovascular disease (CVD). The aim of this study was to assess the 10-year risk of fatal or non-fatal major cardiovascular events (myocardial infarction or stroke) in type-2 diabetes mellitus patients attending a tertiary care centre in Davangere-Karnataka.
Methods: A cross‑sectional study was conducted among diabetics coming to OPD of a tertiary level hospital in Davangere between September 2015-February 2016. 10‑year risk of developing a major (fatal or non-fatal) cardiovascular event was assessed using WHO‑ISH risk prediction charts.
Results: Of the 311 subjects, 181 (58.2%) were females. 139 (44.69%) had low risk ie.< 10%. 93 (29.9%) and 41 (13.81%) had 10-<20% and 20-< 30 % risks respectively. 16 (5.14%) subjects had 30-<40% risk while 22 (7.07%) had ≥40 % risk. Age more than 60 years, smoking and hypertension were significantly associated with a 10-year cardiovascular risk of ≥20%. Those with prehypertension were at significantly higher risk than those with stage II hypertension.
Conclusion: WHO-ISH charts can help in identifying diabetics at high-risk of CVD and could serve as a tool in planning suitable strategies for the estimated CVD burden in the hospital in near future.
References
Global report on diabetes. Geneva: World Health Organiza-tion; 2016.
India. International Diabetes Federation. Available from: http://www.idf.org/membership/sea/india Accessed on 07-04-2017
IDF Diabetes Atlas. 7th edition. Brussels: International Dia-betes Federation; 2015. Available from http://www. diabe-tesatlas.org/ Accessed on 07-04-2017
Taylor F, Huffman MD, Macedo AF, Moore TH, Burke M, Davey Smith G, et al. Statins for the primary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews. 2013; 1: CD004816. Available from: http://doi. wiley.com/10.1002/14651858.CD004816.pub5 Accessed on 06-04-2017
Halvorsen S, Andreotti F, Ten Berg JM, Cattaneo M, Coc-cheri S, Marchioli R, et al. Aspirin Therapy in Primary Car-diovascular Disease Prevention. Journal of the American College of Cardiology. 2014;64(3):319–27.
Akesson A, Larsson SC, Discacciati A, Wolk A. Low-Risk Diet and Lifestyle Habits in the Primary Prevention of Myo-cardial Infarction in Men. Journal of the American College of Cardiology. 2014;64(13):1299–306
Impact of Intensive Lifestyle Intervention on Depression and Health-Related Quality of Life in Type 2 Diabetes: The Look AHEAD Trial. Diabetes Care. 2014;37(6):1544–53.
Chauhan AS, Mukherjee K. Economic burden of coronary heart disease in North India. Int J Non‑Commun Dis 2016;1:18‑25.
Jan S, Lee SW-L, Sawhney JP, Ong TK, Chin CT, Kim H-S, et al. Catastrophic health expenditure on acute coronary events in Asia: a prospective study. Bulletin of the World Health Organization. 2016;94(3):193–200.
WHO/ISH risk prediction charts for 14 WHO epidemiolog-ical sub-regions. Available on http://ish-world.com/ downloads/activities/colour_charts_24_Aug_07.pdf Ac-cessed on 07-04-2017
Otgontuya D, Oum S, Buckley B, Bonita R. Assessment of total cardiovascular risk using WHO/ISH risk prediction charts in three low and middle income countries in Asia. BMC Public Health. 2013;13(1):539. doi: 10.1186/1471-2458-13-539.
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Bethesda: NHLBI Health Information Cen-ter; 2004. Available on https://www.nhlbi.nih.gov/files/ docs/guidelines/jnc7full.pdf Accessed on 07-04-2017
Ghorpade AG, Shrivastava SR, Kar SS, Sarkar S, Majgi SM, Roy G. Estimation of the cardiovascular risk using World Health Organization/International Society of Hypertension (WHO/ISH) risk prediction charts in a rural population of South India. Int J Health Policy Manag. 2015;4(8):531–6.
Bansal P, Chaudhary A, Wander P, Satija M, Sharma S, Girdhar S, et al. Cardiovascular Risk Assessment Using WHO/ISH Risk Prediction Charts In a Rural Area of North India. Journal of Research in Medical and Dental Science. 2016; 4(2):127-31.
Savitharani BB, Madhu B, Renuka M, Sridevi, Ashok NC. Utilization of WHO-ISH 10-year CVD risk prediction chart as a screening tool among supporting staff of a tertiary care hospital, Mysuru, India. Heart India 2016;4:13-6.
Aswin K, Arun GG, Sitanshu S K, Ganesh K. Cardiovascular disease risk factor profiling of group C employees in Jipmer, Puducherry, Journal of family medicine and prima-ry care, 2014; 3(3):255-9.
Shrivastava SR, Ghorpade AG, Shrivastava PS. A Communi-ty-based Cross-sectional Study of Cardiovascular Risk in a Rural Community of Puducherry. Heart Views. 2015; 16(4): 131-6.
Fatema K, Zwar NA,Milton AH,et al. Application of two versions of the WHO/international society of hypertension absolute cardiovascular risk assessment tools in a rural Bangladeshi population. BMJ Open 2015;5:e008140. Availa-ble on http://bmjopen.bmj.com/ Accessed on 30-10-2016
Khanal MK, Ahmed MSAM, Moniruzzaman M, Banik PC, Dhungana RR, Bhandari P, et al. Total cardiovascular risk for next 10 years among rural population of Nepal using WHO/ISH risk prediction chart. BMC Research Notes. 2017;10(1). doi: 10.1186/s13104-017-2436-9
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
The authors retain the copyright of their article, with first publication rights granted to Medsci Publications.