Factors Predicting Treatment Adherence Among Patients with Hypertension: A Systematic Review and Meta-Analysis

Authors

  • Thandar Win Faculty of Nursing, Chulalongkorn University, Bangkok 10330, Thailand
  • Sureeporn Thanaslip Faculty of Nursing, Chulalongkorn University, Bangkok 10330, Thailand; Director of Asian Wisdom Care Research Unit, Chulalongkorn University, Thailand
  • Rapin Polsook Faculty of Nursing, Chulalongkorn University, Bangkok 10330, Thailand

DOI:

https://doi.org/10.55489/njcm.160720255266

Keywords:

Hypertension, Treatment Adherence, Factors, Systematic review, Meta-analysis

Abstract

Background: Through the increased prevalence of hypertension, the notch of following the prescribed anti-hypertensive treatment among these populations is very inadequate, and the unsatisfactory disease control rate. This study systematically reviewed and identified their characteristics of the predicting factors on it and their magnitude.

Methodology: By the Joanna Briggs Institute (JBI) methodology, the included articles were critically appraised and assessed their certainty of evidence with the GRADE guidelines. Four databases (Google Scholar, ScienceDirect, PubMed, and WILEY online) and the keywords of treatment adherence” OR “compliance” AND “determinants” OR "factors" OR "predictors" OR “influences” AND "hypertension" OR “high blood pressure” were applied. The integrated effect sizes (z), 95% confidence intervals (CIs), and I2 index were reported.

Findings: Descriptive correlational and longitudinal designs were included in total 20 studies. The significant predictors were demographic, intrapersonal, interpersonal, condition-related, and health system-related ones. Patients’ self-efficacy, perception, co-morbidity and social support produced the most significant effects. Additionally, various adherence levels to treatment were reported as low to acceptable.

Conclusion: The hypertension society should strengthen their adherence practices by clear instructions and guidance, especially for multimorbid ones, by improving their self-efficacy and perception on their disease, building social support and virtuous patient-provider communication.

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Published

2025-07-01

How to Cite

1.
Win T, Thanaslip S, Polsook R. Factors Predicting Treatment Adherence Among Patients with Hypertension: A Systematic Review and Meta-Analysis. Natl J Community Med [Internet]. 2025 Jul. 1 [cited 2025 Jul. 1];16(07):720-32. Available from: https://njcmindia.com/index.php/file/article/view/5266

Issue

Section

Systematic Review/ Meta Analysis